Metronomic Capecitabine in Stage III Gastric Cancer

Inclusion criteria

• Lower age limit of research subjects 18 years old and upper age limit of 80 years old.
• Be proven to be primary adenocarcinoma of gastric cancer and staged III by pathological evidences
• R0 gastrectomy with D2 lymphadenectomy
• ECOG (ECOG score standard) performance status of 0 or 1 and expected to survive more than 6 months
• No contraindications, including normal peripheral blood routine, liver and kidney function and electrocardiogram （WBC≥3.5 x 109 /L, NEU≥1.2 x 109 /L,PLT≥90 x 109 /L and HGB≥80g/L).

Exclusion criteria

• History of chemotherapy, radiotherapy, immunotherapy or target therapy
• Multiple primary tumors
• Suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, complicated by poorly controlled hypertension, diabetes, mental disorders or diseases
• Unavailable for R0 resection and D2 lymph node dissection.
• Patients with stage IV gastric cancer