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NCT Number: NCT07045870

Methods of Post Operative Analgesia in Patients Undergoing Thyroidectomy

this study aims to compare between effects of lidocaine and ketamine infusion on postoperative analgesia in patients undergoing thyroidectomy.

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Key information

Conditions

Thyroid Disorder Endocrine System Diseases Thyroid Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sohag university hospital

Sohag, Egypt

Location status: Recruiting

Location contact

Magdy M Amin, Professor

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age from 18 to 75 years old
  • both sexes
  • scheduled for thyroidectomy

Exclusion criteria

  • toxic goiter
  • (BMI) exceeding 30 kg / m2
  • un controlled hypertension
  • sever liver or kidney disorders
  • allergy to study drugs
  • hyperthyroidism

Treatment and study plan

group L : will receive lidocaine

Drug

group L : will receive 1.5 mg/kg bolus of iv lidocaine 10 minutes before anaesthesia induction then continuous iv infusion rate 1.5 mg / kg / h

group k : will receive Ketamine

Drug

patients will receive .25 mg / kg bolus of iv ketamine 10 minutes before anaesthesia induction then continuous iv infusion of ketamine at .25 mg /kg /h

group c: will recieve .9% saline

Drug

group c will be injected with equivalent volumes and rates of .9% saline using the same application scheme as the lidocaine and ketamine as a control group

Primary outcomes

  1. the effect of perioperative intravenous lidocaine and ketamine infusion for postoperative analgesia in patients undergoing thyroidectomy

    Time frame: 24 hours posftoperative

    postoperative pain by Numerical Rating Scale (NRS) Zero means no pain and ten means worst pain

Study contacts

Contact information is provided by the study sponsor or research team.

Abdel Rahman H Abdel Rahman, Professor

CONTACT

01120320258

Mario N Ishak, Resident

CONTACT

[email protected]

01210609798

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Effects of Perioperative Intravenous Lidocaine Infusion Versus Ketamine Infusion For Postoperative Analgesia in Patients Undergoing Thyroidectomy : A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 1, 2025
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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