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NCT Number: NCT03752697

Metacognition in Neurological Injury

The purpose of this study is to investigate the trajectory of metacognitive functioning throughout phases of recovery from neurological insult, and to determine its relationship to rehabilitation compliance and functional outcome. It is hypothesized that metacognitive accuracy improves over time, and is a significant predictor of engagement in rehabilitation activities.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Brain Injuries Brain Diseases Central Nervous System Diseases Craniocerebral Trauma Nervous System Diseases Trauma, Nervous System Wounds and Injuries

Age range

19 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Nebraska-Lincoln

Lincoln, Nebraska, 68588-0308, United States

About this study

This study will examine the trajectory of metacognitive functioning through different phases of recovery from neurological insult, and document its relationship to rehabilitation compliance. Individuals currently completing rehabilitation programs and individuals from the community who meet study criteria are invited to participate. After consenting and enrolling in the study, participants complete 2 study sessions: a baseline session, and a follow-up session either at time of completion of rehabilitation program or 3 months later if not in a rehabilitation program. During the study sessions, participants will complete paper-and-pencil and computerized tests of cognition (including metacognitive tasks).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • history of brain and/or spinal cord injury
  • no history of brain or neurological injury/insult (for healthy control group)
  • fluent in spoken and written English
  • adequate gross motor abilities to provide a button push on a keyboard

Exclusion criteria

  • exclusion criteria for healthy controls include:
  • current/past history of psychiatric illness
  • learning disorder
  • developmental disorder
  • diagnosis of Attention Deficit Disorder/Attention Deficit Hyperactive Disorder

Treatment and study plan

metacognitive performance

Behavioral

Paper and pencil/computerized tests of metacognition

Primary outcomes

  1. Change from baseline metamemory performance to completion of rehabilitation

    Time frame: At baseline and at end of length of stay in rehabilitative setting (on average 3 months)

    The computerized metamemory test produces scores that are used to calculate a gamma coefficient, which is a quantitative measure of the individual's metacognitive performance/accuracy.

Secondary outcomes

  1. Change in rehabilitative engagement

    Time frame: At baseline and at end of length of stay in rehabilitative setting (on average 3 months)

    The rehabilitative engagement questionnaire is a clinician-report measure that queries the clinician's perception of their client's participation in rehabilitation services.

Sponsors and collaborators

Lead sponsor

University of Nebraska Lincoln

Other

Collaborators

  • Quality Living, Inc.

Registry information

Official study title

Longitudinal Examination of Metacognition in Neurological Samples

Important dates

Study start
2018
Primary completion
2026
Study completion
2026
First posted
Nov 26, 2018
Registry last updated
Oct 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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