Metabolome and Microbiomic in Fecal Samples

The purpose of this study is to evaluate the effects of storage and handling on fecal samples collected for metabolomic, proteomic and microbiomic and analysis.

Completed

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Key information

Conditions

Infant

Age range

12 month–20 month

Sex eligibility

All sexes

Study type

Observational

Primary location

MassGeneral for Children

Boston, Massachusetts, 02114, United States

About this study

Background

Human fecal collection for clinical or research studies usually occurs at the residence of the subject, an environment not equipped with measures to accommodate proper preparation and storage of samples for microbiome and metabolome analysis.

Aims

To evaluate the effects of storage and handling on fecal samples collected for metabolomic, proteomic and microbiomic and analysis.

Methods

Fecal samples will be collected within several minutes of voiding from healthy infants at the time of diaper change at day-care center.

Samples will be divided into 7 tubes, and subjected to different storage temperatures, before preforming microbial analysis by DNA sequencing, and metabolome analysis by H1NMR spectroscoty.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

healthy
age 12-20 months

Treatment and study plan

Primary outcomes

Microbiome and metabolome yield

Time frame: one month

Sponsors and collaborators

Lead sponsor

Massachusetts General Hospital

Other

Registry information

Official study title

Fecal Samples for Metabolomic and Microbiomic Studies: Effects of Preparation and Storage

Acronym: MicroMet

Important dates

Study start: 2009
Primary completion: 2009
Study completion: 2009
First posted: Jul 13, 2009
Registry last updated: Jul 21, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed