Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)

Inclusion criteria

(Patients)

• Alaska Native or American Indian person by self-report
• eligible for or already receiving services at Southcentral Foundation (SCF)
• age 18 years or older
• daily smoking in the past 30-days
• if other nicotine or tobacco products are used, cigarettes are main product used
• planning to schedule an appointment with the Quit Tobacco Program to seek smoking cessation treatment in the next 30 days
• willing to make a quit attempt within 30 days of enrollment in the Quit Tobacco Program
• willing to have a blood test to inform their treatment
• willing to try a pharmacologic treatment
• willing to provide a saliva sample
• has phone service
• has access to broadband internet on mobile phone at home, work, or other location
• has an Android or iPhone mobile phone compatible with the Smokerlyzer app

(Staff)

• Staff participants of qualitative interviews to assess acceptability and feasibility of the intervention must be a health care professional at Southcentral Foundation (SCF), involved in the care of one of the participants of the study, that is their care team staff; including but not limited to: primary care providers, tobacco treatment specialists/health educators, pharmacists, nurse case managers, behavioral health consultants, certified medical assistants, and lab technicians.

Exclusion criteria

(Patients)

• Participated in the prior study phase
• participated in a cessation program during the past 3 months
• their provider has not approved varenicline in their referral to the Quit Tobacco Program
• has history of serious hypersensitivity or skin reactions to varenicline
• has bleeding disorder or is currently receiving cancer treatment
• questionable capacity or impaired decision-making capacity