Skip to main content
OpenTrials
Completed

NCT Number: NCT02594722

Metabolism and Oxygen Consumption During Functional Electrical Stimulation Cycling in COPD

Chronic Obstructive Pulmonary Disease (COPD) had systemic repercussion and lead to peripheral muscular dysfunction. Muscular atrophy limits aerobic capacity and is a major limitation of daily activity and quality of life. Technologies likes' neuromuscular electrical stimulation (NMES) are currently being adapted and tested to support exercise training.

The investigators hypothesized that functional electrical stimulation cycling improves VO2 and aerobic capacities during exercise compared to endurance training.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

COPD Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Medrinal

Montivilliers, 76290, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • COPD (Stade II, III or IV)
  • Inform consent

Exclusion criteria

  • Pulmonary rehabilitation contraindication
  • Patient with Pacemaker
  • Patient in acute exacerbation
  • Patient with neurologic comorbidity
  • Anemiae

Treatment and study plan

FES-Cycling

Device

Patients performed an endurance tests with functional electrical stimulation during 30 minutes with an oxygen uptake measure.

Classic cycloergometer

Device

Patients performed an endurance tests on classic ergometer during 30 minutes with a sham electrical stimulation with an oxygen uptake measure.

Primary outcomes

  1. oxygen uptake (VO2)

    Time frame: during 30 minutes exercise

Secondary outcomes

  1. Ratio Ventilation/VO2 (Ventilation equivalent for oxygen)

    Time frame: during 30 minutes exercise

    Number of liters of air must be ventilated to consume 1 liter of O2

  2. Ratio Ventilation/VCO2 (Ventilation equivalent for carbon dioxide)

    Time frame: during 30 minutes exercise

    Number of liters of air must be ventilated to reject 1 liter of CO2

  3. cardiac output

    Time frame: during 30 minutes exercise

  4. Muscular fatigue

    Time frame: after 30 minutes exercise

Sponsors and collaborators

Lead sponsor

University Hospital, Rouen

Other

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Nov 3, 2015
Registry last updated
Apr 18, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.