Metabolic Syndrome Diagnosis and Education Trial

Inclusion criteria

Any 3 of the following 5:

• History of hypertension or either systolic blood pressure >125 or diastolic blood pressure >85 mmHg or documented history and receiving treatment for it
• Abdominal circumference ≥40 inches in men or ≥35 inches in women
• Fasting triglycerides ≥ 150mg/dL or receiving treatment for it
• Fasting blood glucose ≥ 100mg/dL but <126mg/dL
• HDL cholesterol <40mg/dL in men or <50mg/dL in women or receiving treatment for it

Exclusion criteria

• Documented diagnosis of metabolic syndrome in the clinical record, if previously seen at Mayo.
• History of coronary artery disease
• Diabetes mellitus, or using an oral hypoglycemic pill for glucose intolerance
• Congestive heart failure
• Familial hypercholesterolemia including familial hypertriglyceridemia,
• Fasting LDL-cholesterol >160 mg/dL
• Fasting triglycerides > 390 mg/dL
• Have systolic blood pressure >160 and diastolic blood pressure >100mg/dL
• History of hypertension with changes in their blood pressure medicines within the last 60 days before enrollment.
• History of dyslipidemia and changes on their lipid lowering agents such as statins, ezetimibe, fibrates or niacin within the last 60 days before enrollment.
• Secondary causes of obesity such as hypothyroidism, Cushing syndrome, or eating disorders
• Pregnant women or women planning to get pregnant during the duration of the study
• Advanced liver disease
• Renal insufficiency
• Having any other major chronic medical condition
• Unable to do their basic chores at home due to musculoskeletal limitations or other factors affecting their functional status.
• Physical activity of more than 60 minutes per week of moderate to intense exercise