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Completed

NCT Number: NCT03938961

Metabolic and Nutritional Characteristics of Long-stayer ICU Patients

The intensive care (ICU) patient population has increasing number of very long ICU stays. Long-stayers are usually defined as requiring more than 1 week of mechanical ventilation and of ICU therapy: little is know about their metabolic characteristics and their relation to outcome. The study aims at describing the demographic, nutritional and metabolic aspects of their stay.

Analysis of 200-250 consecutive patients admitted to the ICU long-stayer program.

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Key information

Conditions

Critically Ill Critical Illness Disease Attributes Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Adult ICU and Burns, University of Lausanne Hospital

Lausanne, Canton of Vaud, 1011, Switzerland

About this study

Data extracted from the computerized ICU system (PDMS): age, Simplified acute physiology score (SAPSII), weight, BMI, Nutrition Risk Score (NRS-2002), daily energy, protein, and glucose intakes, Energy balance, blood glucose (dysglycemia and Glu variability) and lactate, 24hr-insulin (Goal Glu 6-8 mmol/l).

Outcome variables: length of stay (LICU), muscle strength (MRC), vital status at 90 days.

Patients will be followed in detail until ICU discharge and for vital status until day 90 after admission Data will be presented as mean or median, univariate and multivariate analysis will be performed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ICU length of stay > 7 days and enrollment to the long-stayer ICU program

Exclusion criteria

  • Major burns
  • Brain injury
  • Severe neurological condition as primary disease

Treatment and study plan

Primary outcomes

  1. Vital Status

    Time frame: up to 90 days

    Alive or dead at 90 days after ICU admission

Secondary outcomes

  1. Force

    Time frame: up to 90 days

    Muscle strength measured by Medical research Council (MRC) score

Other outcomes

  1. Decubitus ulcer

    Time frame: up to 90 days

    Appearance of decubitus ulcer during ICU stay

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire Vaudois

Other

Registry information

Official study title

Long-stayer Critically Ill Patients: is the Metabolic and Nutritional Therapy in the ICU Creating the Problem?

Acronym: Nutri-ICU-LS

Important dates

Study start
2017
Primary completion
2020
Study completion
2020
First posted
May 6, 2019
Registry last updated
Apr 14, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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