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Completed

NCT Number: NCT04006470

Meta-analysis of Stannous Fluoride and the Effects on Enamel Erosion

The aim of this 5 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices to assess enamel erosion protection in-situ using surface profilometry.

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Key information

Conditions

Enamel Erosion

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Multiple P&G Investigation Clinical Sites

Cincinnati, Ohio, 45040, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects

Treatment and study plan

Stannous Fluoride Dentifrice

Drug

Stannous fluoride (0.454%) dentifrice

Positive control dentifrice

Drug

Positive control dentifrice containing potassium nitrate or arginine.

Negative Control Dentifrice

Drug

Negative control dentifrice containing either sodium fluoride (0.243%) or sodium monofluorophosphate (0.76%)

Primary outcomes

  1. Change from Baseline Surface profilometry

    Time frame: 10 days

    Enamel samples will be measured via profilometry after 10 days of study use.

Sponsors and collaborators

Lead sponsor

Procter and Gamble

Industry

Registry information

Official study title

Bioavailable Stannous Fluoride Dentifrice Meta-Analyses: Effects on Dentine Hypersensitivity and Enamel Erosion

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Jul 5, 2019
Registry last updated
Jul 5, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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