Meshed Vein Graft Patency Trial - VEST

The study hypothesis is that a meshed conduit made of safen vein allows a better patency at mid-long term than a safen vein alone.

To test this hypothesis the investigators plan a prospective, randomized study, comparing grafts to the diagonal, in cases of vessel diameter under 1.5mm. A control angiography will be performed one year after the operation.

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Key information

Conditions

Coronary Artery Disease Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Disease Heart Diseases Myocardial Ischemia Vascular Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

European Hospital, Rome, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Clinical Indication for elective Coronary Artery Bypass Grafting with at least one vein graft
Coronary artery with critical stenosis (over 70%)

Exclusion criteria

Treatment and study plan

External Mesh for vein grafts

Device

Primary outcomes

Patency

Time frame: 6 to 12 months

Patency of graft at CT Scan

Secondary outcomes

Major Adverse Cardiac and Cerebrovascular Events (MACCE)

Time frame: 60 months
Vein graft lumen uniformity

Time frame: 6 to 12 months

Sponsors and collaborators

Lead sponsor

Cardiochirurgia E.H.

Other

Registry information

Official study title

External Mesh of Vein Grafts In Coronary Artery Bypass Grating: Early Patency and Clinical Outcome

Important dates

Study start: 2015
Primary completion: 2019
Study completion: 2020
First posted: May 22, 2013
Registry last updated: Mar 12, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed