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Completed

NCT Number: NCT02609542

Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder

The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect.

The diversity of language developement disorders depends either in the expressive level or in the receptive level leading to divers syndromes and symptoms. These syndromes and symptoms are regrouped under the name of STOL (Specific Troubles of Oral Language).

In the current project the visual exploitation and learning capability of children presenting a STOL condition will be compared to patients with a normal development. The investigator's hypothesis is as follows: STOL patients for whom the STOL disorder is reduced between 4 and 7 years of age will present a better performance at verbal memorisation, compared to patients with a persistent STOL condition after the age of 6.

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Key information

Conditions

Language Development Disorders Communication Disorders Language Disorders Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

45 month–95 month

Sex eligibility

All sexes

Study type

Observational

Primary location

Hôpital St Vincent-de-Paul (GHICL)

Lille, Hauts-de-France, 59000, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for STOL patients:

  • Child aged between 45 and 95 months at inclusion
  • A score > or equal to 5 percentile on the non verbal intelligence test (PM47)
  • Patient diagnosed with STOL by the neuropediatric medical team
  • Coverage of the social insurance
  • Consent form signed by the parents or the legal representative of the child
  • Normal or corrected sight
  • Normal hearing

Inclusion criteria

for control patients:

  • Child aged between 45 and 95 months on the day of inclusion
  • A score > or equal to 5 percentile on the non verbal intelligence test (PM47)
  • Child who did not receive any speech therapy
  • Coverage of the social insurance
  • Consent form signed by the parents or the legal representative of the child
  • Normal or corrected sight
  • Normal hearing

Exclusion criteria

for STOL patients:

  • Mother language other than French
  • Score < to 5 percentile on the non verbal intelligence test (PM47)
  • Child with pervasive developmental disorder

Exclusion criteria

for control patients:

  • Mother language other than French
  • Score < to 5 percentile on the non verbal intelligence test (PM47)
  • Child who received speech therapy

Treatment and study plan

Eye Tracking

Other

Eye tracker will allows the recording of various information concerning eye fixation (number, duration, location) and saccadic eye movement (speed, range, number, duration) in order to determine the interplay between linguistic and visual information processing during tests performance

Other names: visual world paradigm

Primary outcomes

  1. Changes from baseline in the score associated to speech-language outcome measured by a scale grouping results of different questionnaires

    Time frame: 0,12, 24 months

    We will determine if capacities of verbal memory of the children presenting STOL diagnosed at an early stage of their development (before 6 years) are predictive of the evolution of the disorder according to their cognitive profile and more specifically, their language profile as well as their tests performances. To measure the speech language outcome is necessary to take in consideration the score of more than one test performance.

Secondary outcomes

  1. Changes from baseline in the Raven's Progressive Matrices (RPM) test

    Time frame: 0,12, 24 months

    Raven's Progressive Matrices (RPM) is a test often used in educational settings that is comprised of 60 multiple choice questions. This is a nonverbal test in that the questions are comprised of visual patterns. RPM measures the ability to think clearly about complex ideas and the ability to store and recall information.

  2. Changes from baseline in the Peabody Picture Vocabulary Test

    Time frame: 0,12, 24 months

    The Peabody Picture Vocabulary Test measures an individual's receptive (hearing) vocabulary and provides, at the same time, a quick estimate of verbal ability or scholastic aptitude.

  3. Changes from baseline in the number repetition test

    Time frame: 0,12, 24 months

  4. Changes from baseline in the sentences repetition test

    Time frame: 0,12, 24 months

  5. Changes from baseline in the non-words repetition test

    Time frame: 0,12, 24 months

  6. Changes from baseline in the children's eye tracking

    Time frame: 0,12, 24 months

    It is done in order to determine if their is a relation between the evolution of processes involved in verbal memorisation (cognitive mechanisms in charge of data processing).

    Eye tracker will allow the recording of information regarding eye fixation (number, duration, location) and saccadic eye movements (speed, range, number, duration) in order to determine the interplay between linguistic and visual information processing during test performances.

Sponsors and collaborators

Lead sponsor

Lille Catholic University

Other

Registry information

Official study title

Coding and Memorisation of Phonologic Information Among Preschool and School Children With Oral Language Developement Disorder.

Acronym: MEMENTO

Important dates

Study start
2014
Primary completion
2023
Study completion
2023
First posted
Nov 20, 2015
Registry last updated
Dec 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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