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OpenTrials
Completed

NCT Number: NCT02703727

Medication Review Focusing on Anticoagulation Therapy in Swiss Community Pharmacies

Oral anticoagulation therapy (OAC) entails a high potential for adverse events and strict adherence is needed.Thus, medication review and identification of safety issues and knowledge gaps about OAC is critically important. The polymedication check (PMC) is a reimbursed intermediate medication review focusing on adherence and medication management for Swiss primary care. Investigators aime to assess the impact of the PMC extended with a semi-structured interview focusing on OAC.

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Key information

Conditions

Drug Therapy Management

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Pharmaceutical Care Research Group University of Basel

Basel, 4056, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • intake of an oral anticoagulant
  • more than 3 drugs over at least 3 months prior to recruitment
  • german language (written and spoken)
  • medicines use in self management

Exclusion criteria

  • living in a nursing home
  • provision of polymedication check in the past

Treatment and study plan

Extended polymedication check

Behavioral

Behavioral: Medication review

Patients on oral anticoagulants and polypharmacy will receive extended polymedication check to identify Pharmaceutical Care Issues, Adherence Issues, Drug related problems and Knowledge Gaps

The PMC has been implemented in 2010 as a new cognitive service provided by any community pharmacist to patient with polypharmacy (n>3 drugs) on long term conditions (> 3 months) and is reimbursed by swiss health insurance. The semi-structured interview contains questions about knowledge on oral anticoagulation therapy. This extended PMC follows a structured predefined protocol.

As an outcome, pharmacist may install a compliance support e.g. weekly filled pill organizer.

Primary outcomes

  1. Number of Knowledge gaps about oral anticoagulation therapy

    Time frame: 2 Weeks

    Knowledge about oral anticoagulation therapy will be assessed during the extended Polymedication check which includes 8 specific questions on oral anticoagulation knowledge. After 2 Weeks a follow-up telephone interview will be performed and the same 8 questions will be assessed.

Secondary outcomes

  1. Medication possessio ratio (MPR)

    Time frame: 12 Months

    Medication history from pharmacy software will be used to calculate the MPR of all drugs, retrospectively starting 12 months before the extended PMC takes place.

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Collaborators

  • University of Basel

Registry information

Official study title

Durchführung Einer Beobachtungsstudie im Rahmen Einer Masterarbeit Zur Identifikation Von Pharmaceutical Care Issues Bei Patienten, Welche Mit Oralen Antikoagulantien Behandelt Werden

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Mar 9, 2016
Registry last updated
Dec 8, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.