Duke University
Durham, North Carolina, 27710, United States
Completed
NCT Number: NCT06018350
Medication Adherence in Rheumatic Diseases
The investigators will pilot test a clinician-led intervention to improve medication adherence in general rheumatology clinic across a spectrum of rheumatic diseases. The study will assess feasibility, acceptability, and fidelity, and explore signal for improved medication adherence.
Completed
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Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- all providers at Southpoint Rheumatology All patients with a rheumatic disease diagnosis currently prescribed at least one rheumatic medication will be included in the analysis
Exclusion criteria
- new patients, those who are not prescribed any rheumatic disease medications, or do not have available pharmacy refill data
Treatment and study plan
Clinician-led adherence intervention
BehavioralThe clinician will review real time pharmacy refill data during clinic and use effective communication techniques to discuss adherence with the patient
Primary outcomes
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Intervention Feasibility as Measured by Number of Providers Agreeing to Participate
Time frame: 4 weeks
-
Intervention Feasibility as Measured by the Feasibility of Intervention Measure (FIM)
Time frame: 4 weeks
Provider survey based on the Feasibility of Intervention Measure, scores range from 1-5, where 5 is most feasible.
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Intervention Feasibility as Measured by Percent of Visits With EMR Documentation of Providers Reviewing Refills
Time frame: 4 weeks
Calculated for the full population, not per participant.
Secondary outcomes
-
Intervention Acceptability as Measured by the Acceptability of Intervention Measure (AIM)
Time frame: 4 weeks
Provider survey based on the Acceptability of Intervention Measure, scores range from 1-5, where 5 is most acceptable.
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Intervention Acceptability as Measured by the Percentage of Patients Who Report a Positive Feeling After Having an Adherence Conversation With Their Providers
Time frame: 4 weeks
Patient survey will be administered following provider visit.
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Fidelity as Measured by the Number of Participants With Clinicians Conducting the Intervention Components of Reviewing Pharmacy Refills and Using Effective Communication Strategies
Time frame: 4 weeks
This was collected using a EMR Smartphrase where clinicians documented whether they reviewed pharmacy refill data or discussed adherence with patients.
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Fidelity as Measured by the Number of Participants With EMR Documentation of Completing the Intervention Components of Reviewing Pharmacy Refills and Using Effective Communication Strategies
Time frame: 4 weeks
-
Change in MPR (Medication Possession Ratio) as a Percentage for the Entire Sample
Time frame: Baseline to 3 months
MPR is calculated by dividing the number of days all patients were covered by medication by the total number of days in the observation period. This is multiplied by 100 to present a percent change for the entire sample.
Other outcomes
-
Change in MPR (Medication Possession Ratio) as a Percentage
Time frame: Baseline to 6 months
MPR is calculated by dividing the number of days a patient is covered by medication by the total number of days in the observation period. This is multiplied by 100 to present a percent change.
Sponsors and collaborators
Lead sponsor
Duke University
Other
Registry information
Official study title
Improving Medication Adherence in Chronic Rheumatic Diseases
Important dates
- Study start
- 2024
- Primary completion
- 2024
- Study completion
- 2024
- First posted
- Aug 30, 2023
- Registry last updated
- Sep 9, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.