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Recruiting

NCT Number: NCT07000916

Medical Follow-up of New Cases of Polyarthritis in Children and Young Adults

Population:

Juvenile idiopathic arthritis (JIA), rheumatoid arthritis (RA) and seronegative / psoriatic / undifferentiated arthritis (UA), systemic lupus erythematosus (SLE) or diffuse systemic sclerosis dSS).

Naïve to basic treatment OR treated for ≤ 3 months; except for patients with JIA.

These 5 cohorts will be subject to standardized clinical monitoring.

Recruiting

Interested in participating?

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Key information

Conditions

Juvenile Idiopathic Arthritis Arthritis Arthritis, Juvenile Arthritis, Psoriatic Arthritis, Rheumatoid Autoimmune Diseases Bone Diseases Connective Tissue Diseases Diffuse Systemic Sclerosis Immune System Diseases Joint Diseases Lupus Erythematosus, Systemic Musculoskeletal Diseases Psoriasis Psoriatic Arthritis Rheumatic Diseases Rheumatoid Arthritis Scleroderma, Diffuse Scleroderma, Systemic Seronegative Arthritis Skin Diseases Skin Diseases, Papulosquamous Skin and Connective Tissue Diseases Spinal Diseases Spondylarthritis Spondylarthropathies Spondylitis Systemic Lupus Erythematosus

Age range

2 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

This study is proposed by the Rheumatology and Pediatrics departments of the 3 French-speaking Universities.

The first objective will be to include a progressive number of new young patients (≤ 50 years) in order to optimize and standardize care and clinical response objectives. The number of 25% of new incident cases will be sought with an increase of 20% each year during the 5 to 10 years of this project.

Population: JIA, RA/UA, SLE, dSS (American Congres of Rheumatology criteria). Naïve to basic treatment OR treated for ≤ 3 months; except for patients with JIA.

These 5 cohorts will be subject to standardized clinical monitoring and specific objectives that will make it possible to analyze the number of patients with a good control of the disease and/or a clinical remission, defined according to the international criteria.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of juvenile idiopathic arthritis, rheumatoid arthritis and seronegative / psoriatic / undifferentiated arthritis, systemic lupus erythematosus or diffuse systemic sclerosis (ACR criteria).
  • Naïve to basic treatment OR treated for ≤ 3 months; except for patients with JIA.

Exclusion criteria

  • Treated for > 3 months
  • > 50 years old

Treatment and study plan

Primary outcomes

  1. Remission rate or absence of synovitis in Rheumatoid arthritis patients

    Time frame: Through the entire study, during approximately 15 years

Other outcomes

  1. Remission rates improvement in Juvenile arthritis (JIA) patients

    Time frame: Through the entire study, during approximately 15 years

  2. Reduction in damage rate in Systemic Lupus Erythematosus patients

    Time frame: Through the entire study, during approximately 15 years

  3. Inclusion of at least 80% of the incident cases of diffuse Systemic sclerosis

    Time frame: Through the entire study, during approximately 15 years

Study contacts

Contact information is provided by the study sponsor or research team.

Patrick Durez

CONTACT

[email protected]

+32 02 764 53 89

Sponsors and collaborators

Lead sponsor

Université Catholique de Louvain

Other

Registry information

Official study title

Medical Follow-up of New Cases of Polyarthritis in Children and Young Adults. Optimization of Clinical Response, Remission, Quality of Life and Analysis of Prognostic Markers

Important dates

Study start
2013
Primary completion
2028
Study completion
2028
First posted
Jun 3, 2025
Registry last updated
Jun 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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