Medical Expulsive Therapy Post-SWL For Renal Stones

To evaluate the efficacy and stone free rate of placebo versus tamsulosin as medical expulsive therapy post-SWL in patients with renal stone less than 20 mm

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Key information

Conditions

Urologic Diseases Calculi Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Calculi Kidney Diseases Male Urogenital Diseases Nephrolithiasis Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Stone, Kidney Urinary Calculi Urogenital Diseases Urolithiasis

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Urology and Nephrology Center

Al Mansurah, Aldakahlia, 35516, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Renal stone ≤ 20 mm.
Lower calyceal stone ≤ 15 mm

Exclusion criteria

Women with known or suspected pregnancy or breastfeeding.
History of alpa-blockers (more than 7 days prior to study participation)
History of ureteral stricture
Multiple (that is more than 2) stones
Stone in solitary kidney (either anatomically or functionally).
Presence of urinary sepsis.
Estimated glomerular filtration rate < 30 ml/min
Contraindication or allergy to tamsulosin

Treatment and study plan

Tamsulosin

Drug

Tamsulosin 0.4 mg once daily

Placebo

Drug

Placebo once daily

Primary outcomes

Stone free rate defined as patient free of any stone residual

Time frame: at 3 months

assessed by Non-contrast Computed Tomography of Urinary Tract (NCCT-UT)

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Medical Expulsive Therapy Post-SWL For Renal Stones. A Randomized Trial

Important dates

Study start: 2019
Primary completion: 2020
Study completion: 2020
First posted: Sep 2, 2021
Registry last updated: Sep 2, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed