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OpenTrials
Enrolling by Invitation

NCT Number: NCT05501041

Measuring Symptom Relief After Radiofrequency Ablation of the Thyroid

The purpose of this study is to measure the impact of thyroid radiofrequency ablation procedure on patients with thyroid-related symptoms using a modified pre-existing scoring system.

Enrolling by Invitation

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Key information

Conditions

Thyroid Endocrine System Diseases Thyroid Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mayo Clinic Rochester

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Undergoing Radiofrequency Ablation (RFA) for symptomatic thyroid nodule(s).

Exclusion criteria

  • Decline to participate in research.

Treatment and study plan

Primary outcomes

  1. Change in symptoms before and after ablation

    Time frame: Baseline and 1-, 3-, 6-, 12-, 18-, and 24-months following treatment

    Measured using a modified 6-item SYS questionnaire that objectively measures patient symptoms on a scale of 0=none, 1=moderate, 2=severe

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Quantification of Symptom Relief Following Percutaneous Ablation of the Thyroid

Important dates

Study start
2022
Primary completion
2026
Study completion
2028
First posted
Aug 15, 2022
Registry last updated
Sep 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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