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OpenTrials
Completed

NCT Number: NCT04553484

Measuring Cardiovascular Performance and Blood Flow Using Common But Never Compared Methods.

Measuring Cardiovascular Performance Using Common Methods in subjects.

Completed

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Key information

Conditions

D012039 D001775

Age range

45 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Middle Georgia Heart and Vascular Center, Macon, Georgia, United States

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About this study

This study will conduct measurements of cardiovascular performance by echocardiography (Echo), Brain Natriuretic Peptide (BNP) blood serum levels and blood flow by volume plethysmography (VP) in subjects who meet the AHA/ACC criteria for screening for peripheral arterial disease (PAD).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • At least 50 Patients from New York Heart Association (NYHA) Class 1 (One or more AHA Risk Factors, asymptomatic), ≤75% (36) Male, ≥25% (12) Female
  • At least 50 Patients from NYHA Class 2 (symptomatic), ≤75% (36) Male, ≥25% (12) Female

Exclusion criteria

  • Subjects on mechanical ventilation.
  • Subjects who require decisions by a medical power of attorney.
  • Subjects unable to safely perform forced expiration.
  • Subjects with known technically difficult (TDS) trans-thoracic echocardiographic windows.

Treatment and study plan

No intervention

Diagnostic Test

No intervention

Primary outcomes

  1. Feasibility of Performing Echo, BNP, and VP on Human Subjects.

    Time frame: Baseline

    The feasibility of performing three common tests, Echocardiography (Echo), Brain Natriuretic Peptide (BNP) and volume plethysmography (VP), in the same subject was assessed. Each of the 657 participants were submitted to a brief non-invasive blood flow and cardiac performance test (plethysmography (VP) and Echocardiography (Echo)). Each of the 236 participants were subject to blood drawn test, Brain Natriuretic Peptide (BNP).

Sponsors and collaborators

Lead sponsor

Semler Scientific

Industry

Registry information

Important dates

Study start
2020
Primary completion
2021
Study completion
2022
First posted
Sep 17, 2020
Registry last updated
Jul 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.