Measuring Alterations of DNA in Human Blood

The purpose of this research is to evaluate an automated, laser-based technique for measuring DNA damge resulting from radiation. We want to use controlled exposure on cancer patients to help develop a measurement to test people who may have been accidentally exposed to radiation.

Completed

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Key information

Conditions

Neoplasms

Age range

21 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Rochester

Rochester, New York, United States

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male or female, age 21 to 70 years old.
Patient undergoing with anti-neoplastic agent(s) known to have genotoxic activity (e.g., cyclophosphamide, 5-FU, cisplatin, Ara-C.
X-irradiation may be considered, so long as a substantial fraction of red marrow is exposed (e.g., femur or chest/trunk region);
treatment could be ongoing therapy or initial therapy.

Sponsors and collaborators

Lead sponsor

University of Rochester

Other

Collaborators

Litron Laboratories

Registry information

Important dates

First posted: Sep 15, 2005
Registry last updated: Sep 11, 2006

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed