Skip to main content
OpenTrials
Completed

NCT Number: NCT01044979

Measurements of Colloid Osmotic Pressure in Interstitial Fluid and Plasma

The purpose of this study is to evaluate a method of sampling interstitial fluid from subcutaneous sewn wicks.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Colloid Osmotic Pressure

Sex eligibility

All sexes

Study type

Observational

Primary location

Haukeland University Hospital

Bergen, 5021, Norway

About this study

Fluid loss from circulating plasma volume is one of the contributors of oedema formation. Measurement of colloid osmotic pressure (COP) both in plasma and in interstitial fluid can be utilised in planing of fluid therapy in patients with oedema. Different methods of sampling interstitial fluid are well validated in animal models, but not in human. Sampling of interstitial fluid by subcutaneous sewn wicks is a well-known method and can be painful. Local anaesthetics can reduce pain. By comparing interstitial fluid taken from areas with or without application of local anaesthetics, a possible influence in COP values can be detected.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults over 18 years

Exclusion criteria

  • Ongoing illness
  • Medication

Treatment and study plan

Primary outcomes

  1. Colloid osmotic pressure

    Time frame: 60 and 90 minuttes after implanting wicks

Sponsors and collaborators

Lead sponsor

Haukeland University Hospital

Other

Registry information

Official study title

Measurements of Colloid Osmotic Pressure in Interstitial Fluid and Plasma, a Methodological Study

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Jan 8, 2010
Registry last updated
Jul 4, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.