UTMB
Galveston, Texas, 77555, United States
NCT Number: NCT02883075
Multiple studies have compared spinal anesthetic performed supine versus lateral, with varying results, in parturients having elective cesarean section. Needle positioning during spinal placement has also been examined. No positioning techniques have demonstrated definitive superiority for hemodynamic stability.
Investigators propose that following spinal placement in the sitting position if the patient is placed in a lateral position for 90 seconds prior to turning them supine, hemodynamic changes caused by sympathectomy related to the subarachnoid block can be avoided.
This is the first study to examining the influence of position changes after spinal anesthetic placement in the sitting position, which includes hemodynamic variables not previously studied including cardiac output, TPR (total peripheral resistance) and pulse pressure variation (PPV).
Looking for future studies?
Notify Me18 year and older
Female
Interventional
Not applicable
Galveston, Texas, 77555, United States
Cesarean section is chosen when natural spontaneous vaginal delivery is either not possible or when the health of the baby or mother is compromised. Cesarean section may be planned, urgent, or performed emergently when the life of the baby or mother is threatened.
Cesarean section is performed using different anesthetic techniques including: spinal, epidural, combined spinal and epidural, and general anesthesia. Spinal anesthesia is the most common technique chosen due to its relative safety, rapid onset and avoidance of potential complications from general anesthesia. It is the technique of choice for elective cesarean section unless contraindicated. Spinal anesthesia causes sympathetic blockade followed by sensory and motor blockade. Nerve fiber size explains the speed of onset and differential block. The critical moments during spinal anesthesia come as soon as local anesthetic is injected into the subarachnoid space.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Spinal anesthesia in sitting position then 2 minutes in Supine position after spinal anesthetic administration
Spinal anesthesia in sitting position then 2 minutes in the right lateral position after spinal anesthetic administration
Spinal anesthesia in sitting position then 2 minutes in the left lateral position after spinal anesthetic administration
Time frame: Immediately before spinal anesthestic placement through placental delivery
Continuous Heart rate (beats per minute) measurements.
Time frame: Immediately before spinal anesthetic placement through placental delivery
Continuous Blood pressure (mmHg) measurements
Time frame: Number of events spinal anesthetic placement through placental delivery
Nausea and vomiting incidence and anti-emetic administration with time stamps will be documented.
Time frame: Number of events spinal anesthetic placement through placental delivery
Anti-emetic administration with time stamps will be documented.
Time frame: Spinal anesthetic placement through placental delivery
Number of vasopressor use events will be monitored and recorded.
Time frame: Spinal anesthetic placement through placental delivery
All vasopressor administrations with time stamps will be documented.
Time frame: Spinal anesthetic placement through placental delivery
Continuous Cardiac output (L/min) measurements
Time frame: Spinal anesthetic placement through placental delivery
Continuous Stroke volume (mL) measurements
Time frame: Spinal anesthetic placement through placental delivery
Continuous TPR (total peripheral resistance, dynes*sec/cm3)measurements
The University of Texas Medical Branch, Galveston
Other
Measurement of Hemodynamic Variables Under Spinal Anesthesia in a Patient Undergoing Cesarean Section With Varied Positioning - a Comparative Study
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT01699243
Anesthesia, Pregnancy
Aurora, Colorado, United States
View Trial DetailsNCT07542197
Anesthesia, Behavior
Bordeaux, France
View Trial DetailsNCT07725549
Birth Weight, Body Weight
Purwodadi Grobogan, Central Java, Indonesia
View Trial DetailsNCT02447159
Behavior, Blood-Borne Infections
Eket, Akwa Ibom State, Nigeria
View Trial Details