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Completed

NCT Number: NCT01292148

Measurement of Core Temperatures During Therapeutic Hypothermia

The purpose of this study is to determine that the measurements of rectal and bladder temperature are correctly consistent with core temperature by using the pulmonary artery catheter during therapeutic hypothermia; rapid cooling, maintenance, and slow rewarming phase.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Seoul National University Boramae Hospital

Seoul, 156-707, South Korea

About this study

The guidelines of therapeutic hypothermia(TH)are rapid cooling, from normothermia to mild hypothermia(32~34 degree), maintenance, and slow rewarming phase. If core temperature maintained below 32 degree during TH, som complications will be developed, such as arrythmia, hypotension, cold diuresis, coagulopathy, and so on. Therefore correct measurement of core temperature during TH is very important process for successful post cardiac arrest care. we will know that rectal or bladder temperature are really reflect the core temperature during TH for post cardiac arrest care, especially rapid cooling phase, maintenance phase, and slow rewarming phase, respectively.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Out of cardiac arrest patient who is 18 years old.
  • Mean arterial pressure must be over 65 mmHg after return of spontaneous circulation.
  • Family consent to this study.

Exclusion criteria

  • In hospital arrest.
  • Arrest due to trauma
  • Arrest due to intracranial hemorrhage.
  • Below 30 degree at initial core temperature.
  • Pregnancy.
  • Family do not agree with our study.
  • Active bleeding patient.

Treatment and study plan

Primary outcomes

  1. Difference of core temperature between rectum, bladder, esophagus and pulmonary artery

    Time frame: During 24 hour

Sponsors and collaborators

Lead sponsor

Seoul National University Hospital

Other

Collaborators

  • SMG-SNU Boramae Medical Center

Registry information

Official study title

Core Temperature Measurement in Therapeutic Hypothermia: Tympanic Membrane, Bladder and Rectal Versus Pulmonary Artery Methods

Acronym: TH

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Feb 9, 2011
Registry last updated
Jul 21, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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