Skip to main content
OpenTrials
Completed

NCT Number: NCT07403045

McGill Strengthening With and Without Integrated Neuromuscular Inhibition Technique in Piriformis Syndrome

The study was conducted to determine the effects of McGill strengthening exercises program with and without integrated neuromuscular inhibition technique on pain, range of motion and function in patients with piriformis syndrome.

Completed

Looking for future studies?

Notify Me

Key information

Age range

25 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mumtaz Bakhtawar Memorial Trust Hospital, Mustafa Town

Lahore, Punjab Province, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Both genders with age ranged from 25 and 45 years
  • Sedentary
  • Non-traumatic
  • Idiopathic
  • External tenderness near the greater sciatic notch
  • Pain for more than 1 month's duration
  • NPRS ranging from >3 to ≤ 6
  • Positive results on three of the following five tests:
  • FAIR
  • Beatty
  • Laségue
  • Pace
  • Freiberg

Exclusion criteria

  • Acute low back pain and/or acute lumbar radiculopathy
  • History of Stroke or any other neurological disorders
  • Recent buttock trauma
  • Inflammatory, infectious or tumor diseases
  • Severe vascular disease
  • Osteoporosis
  • Pregnancy

Treatment and study plan

McGill strengthening exercises program

Other

These exercises were divided into 3 phases, each lasting 2 weeks. Patients performed 4 repetitions of each exercise during 1st and 2nd week at each hospital visit. Then, increased by 4 repetitions every 2 weeks for up to 6 weeks. These exercises were performed with a maximum of 12 repetitions with a 1-minute of rest interval between each exercise. These exercises were performed by patients at each clinical visit, 3 days per week for total of 6 weeks.

Integrated Neuromuscular Inhibition technique

Other

This technique was applied at piriformis muscle. The procedure was repeated 3 times for up to 10 minutes at each clinical visit. This intervention was performed 3 days per week for total of 6 weeks.

Standardized Physiotherapy Treatment

Other

These exercises were performed by patients at the end of each hospital visit (3 days per week for total of 6 weeks) and also at home twice a week during the 2 months follow-up period after treatment ends.

  • Continuous-mode ultrasound therapy was applied at a frequency of 1 MHz and an intensity of 1.0 W/cm² for 3 minutes to the tender or trigger points on the posterior aspect of the pelvis.
  • A hydrocollator pack (40°C) was applied for 10 minutes at lumbopelvic region.
  • Piriformis, hamstring/calf stretching was performed progressively in phases.
  • Phase 1 consists of weeks 1 and 2 with 1 set of 3 repetitions with 30 seconds hold per day.
  • Phase 2 consists of weeks 3 and 4 with 2 sets of 3 repetitions with 30 seconds hold per day.
  • Phase 3 consists of weeks 5 and 6 with 2 sets of 3 repetitions with 30 seconds hold twice per day.
  • Follow-up period consists of 2 sets of 3 repetitions with 30 seconds hold twice per day.

Primary outcomes

  1. Numeric Pain Rating Scale

    Time frame: From enrollment to 6 weeks of intervention with follow-up at 14 weeks.

    Numeric Pain Rating Scale (NPRS) was used to assess the patient's pain intensity. This scale ranges from 0 to 10, where 0 indicates "no pain" and 10 indicates "worst pain.

Secondary outcomes

  1. Range of Motion (Hip Abduction)

    Time frame: From enrollment to 6 weeks of intervention with follow-up at 14 weeks.

    The universal goniometer was used to assess hip abduction range of motion.

  2. Range of Motion (Hip Internal Rotation)

    Time frame: From enrollment to 6 weeks of intervention with follow-up at 14 weeks.

    The universal goniometer was used to assess hip internal rotation range of motion.

  3. Lower Extremity Functional Scale

    Time frame: From enrollment to 6 weeks of intervention with follow-up at 14 weeks.

    Lower Extremity Functional Scale was used to assess the patient's functional status. Maximum score of this scale is 80. The greater the score, the lower the disability.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects of McGill Strengthening Exercises Program With and Without Integrated Neuromuscular Inhibition Technique on Pain, Range of Motion and Function in Patients With Piriformis Syndrome

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 11, 2026
Registry last updated
Feb 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.