Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06525285

MCAF and EMD With and Without CTG Wall Technique for the Treatment of Class III and IV Gingival recessions-a Randomized Control Trial

Research is to compare and evaluate the clinical outcomes of the Connective tissue graft wall technique with modified coronally advanced flap to improve root coverage and clinical attachment levels in Miller's class III and IV gingival recession.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Research is to compare and evaluate the clinical outcomes of the Connective tissue graft wall technique with modified coronally advanced flap to improve root coverage and clinical attachment levels in Miller's class III and IV gingival recession. The objectives is to assess the probing pocket depth reduction, clinical attachment level gain, patient esthetic evaluation, complete root coverage and mean root coverage. the control group will be treated with modified coronally advanced flap with connective tissue graft and enamel matrix derivative and the study group will be treated with modified coronally advanced flap with connective tissue graft wall and enamel matrix derivative. The total number of participants included will be 24 (Control-12; Study-12) with a 6 month follow up.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants aged 18-60 years
  • Systemically healthy individuals
  • Participants with Miller's Class III and IV or Cairo's RT3 gingival recession in maxillary and mandibular anteriors.
  • Participants with Nordland and Tarnow's papillary recession of either I, II or III.
  • Presence of interdental PPD, CAL and recession
  • Radiographic evidence of interdental bone loss
  • No prior experience of root coverage procedures
  • Able to achieve good oral hygiene and control gingivitis in the whole of the dentition (FMPS < 25% and FMBS < 25%).

Exclusion criteria

  • Grade III mobile teeth
  • Pathologically migrated teeth
  • Endodontically treated teeth
  • Open contacts
  • Pregnancy and lactating women
  • Participants with systemic conditions
  • Untreated periodontitis
  • Persistence of uncorrected gingival trauma from tooth brushing
  • Self-reported current smoking
  • Presence of medical contraindications to elective surgery

Treatment and study plan

Connective tissue graft wall technique

Procedure

Harvested connective tissue graft will be placed over the exposed root surface like a wall to cover the gingival recession

Other names: Connective tissue graft technique

Primary outcomes

  1. Root coverage

    Time frame: 6 months

    Mean root coverage Cairo's RT3 gingival recession treated with MCAF + CTG wall + EMD technique is non-inferior to MCAF + CTG + EMD in terms of root coverage.

Secondary outcomes

  1. Gingival health and evaluation

    Time frame: 6 months

    clinical attachment level

Study contacts

Contact information is provided by the study sponsor or research team.

Prabhuji MLV, MDS

CONTACT

[email protected]

9448057407

Sponsors and collaborators

Lead sponsor

Krishnadevaraya College of Dental Sciences & Hospital

Other

Registry information

Official study title

Modified Coronally Advanced Flap and Enamel Matrix Derivative With and Without Connective Tissue Graft Wall Technique for the Treatment of Class III and IV Gingival recessions-a Randomized Control Trial

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jul 29, 2024
Registry last updated
Jul 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.