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Completed

NCT Number: NCT02098668

Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEON

Development of a bio-mathematical model of the human female cycle

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Key information

Conditions

Polycystic Ovary Syndrome Adnexal Diseases Brain Diseases Central Nervous System Diseases Cysts Endocrine System Diseases Endometriosis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Gonadal Disorders Hyperpituitarism Hyperprolactinemia Hypothalamic Diseases Infertility Neoplasms Nervous System Diseases Ovarian Cysts Ovarian Diseases Pituitary Diseases Urogenital Diseases

Age range

18 month–43 year

Sex eligibility

Female

Study type

Observational

Primary location

University Hospital Zurich, Division of Reproductive Endocrinology

Zurich, Canton of Zurich, 8091, Switzerland

About this study

From hormonal measurements throughout 1-2 menstrual cycles in women with and without endocrinological pathology a mathematical model of the human menstrual cycle will be generated. The model will serve to predict development of the cycle including ovulation as well as to better understand the pathophysiology of endocrinological disorder. In a second step current treatment protocols for fertility treatment will be integrated into the model in order to optimize treatment outcome.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women during their reproductive phase, no hormonal therapy

Exclusion criteria

  • Amenorrhoae

Treatment and study plan

Fertility treatment

Other

Fertility treatment

Primary outcomes

  1. Hormonal parameters

    Time frame: 3 years

    Development of a mathematical model of the menstrual cycle

Secondary outcomes

  1. Dynamics of fertility treatment

    Time frame: 2 years

    Mathematical model to improve fertility treatments

Other outcomes

  1. Dynamics of gyneco-endocrinological diseases

    Time frame: 3 years

    To better understand the pathophysiological mechanisms in endocrinological diseases

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Registry information

Official study title

Model Driven Computation for Infertility Related Endocrinological Diseases - PAEON

Acronym: PAEON

Important dates

Study start
2013
Primary completion
2016
Study completion
2016
First posted
Mar 28, 2014
Registry last updated
Sep 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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