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OpenTrials
Completed

NCT Number: NCT03088228

Maternal Periodontal Status and Cytokines in Preeclampsia

Background: The purpose of this study is to examine the relationship between maternal preeclampsia and periodontal parameters and the correlation of these two disorders with maternal gingival crevicular fluid levels (GCF) of interleukin (IL)-35, interleukin-37 and interleukin-6. The investigators also investigated their relation to the severity of preeclampsia.

Methods: 82 preeclamptic women were recruited to the study (29 healthy pregnant women, 30 mild preeclamptic patient, 23 severe preeclamptic patient ). The clinical periodontal parameters and GCF samples were collected in the first day of puerperium.

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Key information

Conditions

Preeclampsia Female Urogenital Diseases and Pregnancy Complications Hypertension, Pregnancy-Induced Mouth Diseases Periodontal Diseases Pre-Eclampsia Pregnancy Complications Stomatognathic Diseases Urogenital Diseases

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged between 18 and 45 years
  • 25 and 40 weeks of gestation.
  • Healthy pregnants, mild and severe preeclampsia

Exclusion criteria

  • Patients with accompanying diseases
  • multiple gestations
  • congenital abnormalities were excluded from the study.

Treatment and study plan

gingival crevicular fluid collection

Diagnostic Test

Primary outcomes

  1. maternal periodontal clinical parameters and IL-37 and IL-35 and IL-6 levels

    Time frame: 6 months

    IL-37 IL-35 and IL-6 levels in maternal gingival crevicular fluid levels between the three groups

Sponsors and collaborators

Lead sponsor

Hacer Sahin Aydinyurt

Other

Registry information

Official study title

Maternal Periodontal Status and Gingival Crevicular Fluid Levels of Interleukin-6, Interleukin-35, and Interleukin-37 in Preeclampsia

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Mar 23, 2017
Registry last updated
Sep 28, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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