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OpenTrials
Completed

NCT Number: NCT05882942

Matcha Green Tea Effects at Rest and During Moderate-intensity Exercise in Females

Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

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Key information

Conditions

No Condition

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Mark Willems, Chichester, West Sussex, United Kingdom

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About this study

Intake of the catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. EGCG is the most abundant and potent bioactive compound (50-80% of the total catechin content) found in Matcha green tea (MGT) and is usually consumed as a drink or in a capsulated from unfermented tea leaves. MGT polyphenols have antioxidant and anti-inflammatory properties, providing numerous health benefits, such as the reduced risk of type 2 diabetes and obesity. MGT supplementation (3g over a 24hr period) has been shown to enhance fat oxidation during 30-min brisk walking as well as lower respiratory exchange ratio in females. Understanding the effectiveness of the bioactive compounds found in natural food sources in improving human health is key to informing the general population and the public health policies preceding them; the daily consumption of drinks and food naturally high in EGCG content could be recommended as an essential part of a healthy lifestyle. This research will expand the insight on Matcha green tea supplementation address the effect on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy
  • non-smokers
  • not taking any supplements
  • no known allergy to green tea

Exclusion criteria

  • smokers
  • known high blood pressure
  • on medication

Treatment and study plan

Matcha green tea

Dietary Supplement

This is the condition with the Matcha green tea

Placebo

Dietary Supplement

This is the condition with the placebo

Primary outcomes

  1. Heart rate variability

    Time frame: Three weeks

    Measurement of root mean square of standard deviation of RR intervals

  2. Carbohydrate oxidation

    Time frame: Three weeks

    Measurement of carbohydrate oxidation in grams/minute

  3. Fat oxidation

    Time frame: Three weeks

    Measurement of fat oxidation in grams/minute

  4. Cardiac output

    Time frame: Three weeks

    Measurement of cardiac output in liters per minute

  5. Stroke volume

    Time frame: Three weeks

    Measurement of stroke volume in milliliters

  6. Total peripheral resistance

    Time frame: Three weeks

    Measurement of total peripheral resistance in (mmHg x min) / mL

Sponsors and collaborators

Lead sponsor

University of Chichester

Other

Registry information

Official study title

Effects of Matcha Green Tea on Heart Rate Variability, Substrate Oxidation and Cardiovascular Response at Rest and During Moderate-intensity Exercise in Females

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
May 31, 2023
Registry last updated
May 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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