Mastectomy With Retention of the Nipple-areola Complex, Robot-assisted or Not, and / or Immediate or Seconday Reconstruction by Latissimus Dorsi Flap, Robot-assisted or Not.

Phase III, non-randomized, monocentric, observational, prospective trial. It is planned to recruit a total of 480 patients, including 240 patients receiving mastectomy with preservation of the nipple-areola complex and 240 patients with a reconstruction with latissimus dorsi flap, or in immediate reconstruction, or during secondary reconstruction.

Inclusion criteria

• Age ≥ 18 years old,
• Signed consent to participate,
• Women with breast cancer over 18 or at high risk of breast cancer (BRCA 1-2 mutations, PALB2, extensive border lesions)
• Mastectomy with conservation of the areolo-mammary plaque, or mastectomy without conservation of the areolo-mammary plaque and conservation of the skin case
• Mastectomy without conservation of the areolo-mammary plate, immediate breast reconstruction by prosthesis,
• immediate breast reconstruction by autologous latissimus dorsi flap
• immediate breast reconstruction by latissimus dorsi flap and prosthesis,
• secondary breast reconstruction by latissimus dorsi flap
• Affiliation to, or beneficiary of, a social security scheme.

Exclusion criteria

• Patient under 18,
• Pregnant woman or likely to be (without effective contraception) or breastfeeding,
• Person in emergency situation, adult person subject to a legal protection measure (adult under guardianship, curatorship or safeguard of justice), or out of state to express his consent,
• Inability to submit to medical follow-up for the trial for geographic, social or psychological reasons.