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NCT Number: NCT05264051

MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease

The purpose of the study is to study the muscle assessment score (MAsS, utilizing MRI, as an objective measure of frailty and muscle composition to serve as a predictor of morbidity and mortality in patients with liver disease.

Recruiting

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Key information

Conditions

Liver Diseases Digestive System Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

Prospective study of patients seen at the Univ. of Chicago Medical Center hospital and ambulatory clinics. The assessment of the MAsS score will require an additional 8-10 minutes in the MRI for each patient already undergoing MRI exam.

Four groups of pts. who are already scheduled for MRI for routine clinical purposes will be evaluated.

  • Pts. hospitalized with acute hepatic decompensation for whom MRI is otherwise indicated for clinical evaluation.
  • Pts. with hepatobiliary neoplasia
  • Pts.undergoing transjugular portosystemic shunt (TIPS) placement
  • Pts. with chronic liver disease undergoing magnetic resonance elastography for routine monitoring

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who are already scheduled for an MRI for routine clinical purposes will be evaluated

Exclusion criteria

  • <18 yrs. of age

Treatment and study plan

Primary outcomes

  1. Waitlist Mortality

    Time frame: Measured up to 10 years out from enrollment

    Death prior to liver transplant or delisting from enrollment in the study

Study contacts

Contact information is provided by the study sponsor or research team.

Maria Newsome

CONTACT

[email protected]

773-702-2788

Omar Jamil, MD

CONTACT

[email protected]

847-373-2360

Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Registry information

Important dates

Study start
2022
Primary completion
2027
Study completion
2027
First posted
Mar 3, 2022
Registry last updated
Jan 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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