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NCT Number: NCT06960434

Mapping Obesity-related Subtypes And Interconnected Clusters

In the Netherlands, about half of all adults are currently living with overweight. This number is expected to rise to as much as 64% by the year 2050, especially among younger adults aged 18 to 44. Overweight and obesity increase the risk of chronic conditions such as heart disease, diabetes, and joint problems. However, there is no single cause behind these issues. Instead, they result from a complex combination of factors - including nutrition, physical activity, sleep, stress, income, environment, and even air quality. These factors often influence each other and vary from person to person.

This study aims to better understand these patterns and connections. By analyzing large sets of data, researchers are identifying different subtypes of people with overweight or obesity. These subtypes reflect groups of individuals who share similar personal, lifestyle, and environmental characteristics. Understanding these differences makes it possible to develop more personalized lifestyle advice and support. That way, care and prevention efforts can be better tailored to what people actually need and what works best for them in practice. Experts from various fields are helping interpret the results, so that scientific insights can be translated into practical solutions for individuals, communities, and healthcare settings.

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Key information

About this study

Overweight and obesity are increasingly prevalent in the Netherlands. Obesity-related health issues are complex and influenced by multiple interacting variables, including personal behaviors, socioeconomic status, environmental characteristics, and health conditions. This study seeks to validate and enrich the results of an ongoing exploratory data analysis by involving experts in the interpretation of identified factor clusters related to BMI categories.

This mixed methods study includes a quantitative component (an online survey) and a qualitative component (expert panel group discussions). Experts are recruited through purposive and snowball sampling and participate in interpreting variable clusters, assessing associations, and drawing conclusions on implications for further research and practical application.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • researchers or professionals with expertise in obesity, lifestyle, environment, psychosocial or medical factors;
  • experience in data interpretation and/or public health;
  • able to communicate in Dutch;
  • willing to participate in the online survey and/or expert panel meeting

Exclusion criteria

  • no relevant domain expertise;
  • inability to give informed consent

Treatment and study plan

Primary outcomes

  1. Expert-perceived relationships between identified factors and BMI and expert assessment on identified data-clusters.

    Time frame: Baseline

    A self-developed questionnaire will be used to investigate and describe expert opinions on (1) the perceived relationsships between specific factors and BMI and (2) the expert assessment regarding data-clusters within BMI categories that has been identified in a previous study. First, the experts are invited to respond to the following question "Do you recognise a relationship between these characteristics and BMI?" on a 3-point likert scale: (1) No, I see absolutely nog relationship. (2) Yes, there may be a relationship, (3) Ik do not know. There will be space for a note. Second, identified data-clusters will be described. The experts are invited to give a brief interpretation of these clusters from their own area of expertise in an open question.

Secondary outcomes

  1. Expert interpretation of within-cluster relationships and inter-cluster differences

    Time frame: One week after baseline

    An expert panel focus group discussion will be organized using different co-creation methods to further explore on the data-clusters within the BMI categories. By having experts from different fields share knowledge and interpretations, we expect to arrive at descriptions of specific subgroups within different BMI categories and about implications for further research and clinical implications (qualitative data-analysis).

Study contacts

Contact information is provided by the study sponsor or research team.

Iris M Kanera, PhD

CONTACT

[email protected]

+642476766

Sponsors and collaborators

Lead sponsor

Zuyd University of Applied Sciences

Other

Collaborators

  • LIME Limburg Measures
  • Statistics Netherlands (CBS)

Registry information

Official study title

Systemic Interpretation of Personal and Environmental Characteristics in Overweight and Obesity: From Data Patterns to Practical Interventions

Acronym: MOSAIC

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 7, 2025
Registry last updated
May 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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