Mapping Human Muscle Satellite Cell Fat… | Clinical Trial

Key information

Conditions

Flaccid Muscle Tone Muscle Hypotonia Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–29 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Purdue University - Stone Hall 700 W State St

West Lafayette, Indiana, 47907, United States

About this study

The aim of this study is to obtain human muscle samples for cell culturing to analyze muscle cell development in real-time to uncover factors that influence growth.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

-Inclusion Criteria:

men 20-29 yrs
BMI between 20 and 34.9
Fasting Glucose <110 mg/dL
Blood Pressure <160/100mm Hg
Non-Diabetic
LDL-Cholesterol <160mg/dL
Triacylglycerol <400 mg/dL
Makers of kidney, liver, and heart functions within 10% of clinical normalcy
<1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months

Exclusion criteria

men <20or>29 yrs

BMI between <20 and >34.9
Fasting Glucose >110 mg/dL
Blood Pressure >160/100mm Hg
Non-Diabetic
LDL-Cholesterol >160mg/dL
Triacylglycerol >400 mg/dL
Pre-existing kidney or liver conditions

-->1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months

Currently taking prescribed blood thinners

Treatment and study plan

Muscle biopsy

Procedure

a muscle sample will be taken from the mid-thigh (Vastus Lateralis) and analyzed

Primary outcomes

Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging

Time frame: <10 hrs

this study is to obtain human muscle samples for cell culturing which will be exposed to a novel real-time imaging technique in order to elucidate factors that influence muscle satellite cell growth.

Sponsors and collaborators

Lead sponsor

Purdue University

Other

Registry information

Official study title

Mapping Human Muscle Satellite Cell Fate By Real-Time

Acronym: S48

Important dates

Study start: 2016
Primary completion: 2016
Study completion: 2016
First posted: Feb 18, 2016
Registry last updated: Jun 20, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed