Manipulation of Dietary Protein and the Anabolic Response

In the present study, the effect of habitual dietary protein on the anabolic response will be investigated.

Completed

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Key information

Conditions

Focus: Anabolic Response to Food Intake in Young Individuals Atrophy Condition Relevance: Skeletal Muscle Health, Sarcopenia Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Sarcopenia Signs and Symptoms

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Males
Aged between 18-35 years
Healthy, recreationally active
BMI < 30 kg/m2

Exclusion criteria

Smoking
Allergies to milk proteins (whey or casein)
Vegetarians
Diagnosed GI tract diseases
Female
Arthritic conditions
A history of neuromuscular problems
Previous participation in amino acid tracer studies
Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications

Treatment and study plan

High protein intake

Dietary Supplement

Placebo Comparator

Other

No protein intake

Other names: control group

Primary outcomes

Muscle protein fractional synthetic rate following protein ingestion

Time frame: 3 hours

The ability of the muscle to synthesise new proteins will be assessed over a 3 h period following protein ingestion and will be compared between groups. This only occurs on one occasion.

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Registry information

Official study title

The Manipulation of Dietary Protein Intake on the Anabolic Response in Healthy Young Men

Acronym: PRO-ADAPT

Important dates

Study start: 2013
Primary completion: 2015
Study completion: 2017
First posted: Mar 29, 2013
Registry last updated: Mar 22, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed