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NCT Number: NCT06880341

Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease

The goal of this study is to study the incidence of post-operative Transient Neurologic Events (TNEs) within 30 days postoperatively, as assessed by clinical neurological scales, binned by week. Collect data on all interventions and assessments performed during the recovery post surgery up to 30 days, to understand what factors might cause Transient Neurologic Events (TNEs) and determine how these can be reduced in Moyamoya subjects post surgery.

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Key information

Conditions

Moya Moya Disease Arterial Occlusive Diseases Brain Diseases Cardiovascular Diseases Carotid Artery Diseases Central Nervous System Diseases Cerebral Arterial Diseases Cerebrovascular Disorders Intracranial Arterial Diseases Moyamoya Disease Nervous System Diseases Vascular Diseases

Age range

3 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Moyamoya Disease (MMD) patients undergoing direct extracranial-intracranial (ECIC) bypass. Patients above the age of 3 years old are eligible for the study

Exclusion criteria

  • Renal dysfunction, electrolyte disturbances neuromuscular disorders including Myaesthenia Gravis, heart block

Treatment and study plan

Standard of care

Other

Standard of care treatment of Transient Neurologic Events (TNEs) as needed

Primary outcomes

  1. Transient Neurologic Events (TNEs)

    Time frame: 30 days post-surgery

    Number of Incidence of post-operative Transient Neurologic Events (TNEs) within 30 days postoperatively, as assessed by clinical neurological scales (e.g., NIH Stroke Scale, Modified Rankin Scale), binned by week.

Study contacts

Contact information is provided by the study sponsor or research team.

Anthony Bet

CONTACT

[email protected]

Jinendra Ekanayake

CONTACT

[email protected]

650-660-1266

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Registry information

Official study title

MagNETs- Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease

Acronym: MagNETs

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Mar 17, 2025
Registry last updated
May 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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