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OpenTrials
Completed

NCT Number: NCT06873295

Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Unit in Subjects Over and Under 75 Years

The management of these often frail elderly patients, with more comorbidities and declining functional capacities, is more complex and justifies a specific, tailored approach.

Age is also associated with an increasing prevalence of gallstones. The disadvantages of "cold" surgery (longer hospital stay, higher cost, risk of disease recurrence in the interim, difficult surgery with more scar tissue due to repeated inflammation) have to be weighed against the high operative risk in the case of emergency surgery, leading to strict criteria for early cholecystectomy.

These criteria are rarely met in geriatric patients, who thus enter a hospital cycle whose impact on morbidity and mortality, as well as on loss of autonomy, has been demonstrated in this population. What's more, the deteriorating general condition of frail elderly patients means that a number of them end up being definitively rejected for surgery, despite an initial strategy of cold cholecystectomy.

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Key information

Age range

19 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Simonet Anne Clarisse

Nîmes, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over 18 years of age.
  • Diagnosis of acute cholecystitis.
  • Hospitalization in the digestive surgery department and geriatric perioperative unit of Nîmes University Hospital.

Exclusion criteria

  • Patients under 18 years of age.
  • Opposition of the patient to his inclusion in the study after sending the letter of information and non-opposition.

Treatment and study plan

Primary outcomes

  1. Rate of patients with an initial cold cholecystectomy strategy who did not undergo surgery, died or underwent emergency surgery

    Time frame: Up to 6 months, from date of first collection to date of end of collection

    Percentage

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Official study title

Evaluation of the Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Intraoperative Unit in Subjects Over and Under 75 Years of Age

Acronym: GERBILLE

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Mar 12, 2025
Registry last updated
Mar 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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