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OpenTrials
Completed

NCT Number: NCT02892227

Management of Acute Heart Failure: Contribution of Ultrasound Daily "in Bed Patient" Adjustment on Therapy With Impact Measure on re Hospital Rate During 30 Days

Our hypothesis: a daily bedside echocardiographic assessment, protocolized, simple and reproducible estimation of filling pressures with an evaluation of mitral inflow and the inferior vena cava, allow a more reliable estimate of the true blood volume of the patient and thus lead to a therapeutic adjustment more suitable.

This therapeutic adjustment closer to patient's needs would impact fewer readmissions at 30 days and mortality, less alteration of biological parameters myocardial, kidney and liver.

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Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU Arnaud de Villeneuve, Montpellier, France

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

The patient or his representative must be given free and informed consent and signed consent.

  • The patient must be affiliated or beneficiary of a health insurance plan.
  • The patient is available for a follow-up 6 months.
  • The patient is of age or older (>) 18.
  • Patients hospitalized for acute heart failure who received at least 40mg of furosemide IV.
  • Patient with impaired LVEF <50%.
  • Patient with Nt-proBNP values> 1200pg / ml.

Exclusion criteria

  • The subject takes part in another study.
  • The subject is exclusion period determined by a previous study.
  • The subject is under judicial protection.
  • The subject or his representative refuses to sign the consent.
  • It is not possible to give the subject or his representative informed information.

Non-inclusion criteria for those diseases or conditions associated (s) interfere (s):

  • The patient is pregnant or is breastfeeding.
  • The patient is already included in a surveillance program (PRADO, OSICAT).
  • Patient with a mechanical or biological mitral prosthesis.
  • History of mitral stenosis.
  • severe valvular surgery with maturity in months (<30 days).
  • chronic renal impairment on dialysis.
  • High grade AV block (AVB and BAV3 2/1).
  • Hypertrophic cardiomyopathy.
  • Cardiogenic shock.
  • Contraindications to furosemide.

Treatment and study plan

Transmitral flow estimation

Procedure

Estimation of the transmitral flow of the inferior vena cava and its variations

Primary outcomes

  1. rehospitalization

    Time frame: 30 days

Secondary outcomes

  1. mortality

    Time frame: 6 months

  2. worsening heart failure

    Time frame: during hospitalization

  3. average length of stay

    Time frame: during hospitalization

  4. alteration of biological parameters myocardial, kidney and liver

    Time frame: Hospital discharge +7 days, Hospital discharge +30 days

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Official study title

MANAGEMENT OF ACUTE HEART FAILURE: THE CONTRIBUTION OF DAILY 'BEDSIDE' ULTRASOUND TO THERAPEUTIC ADJUSTMENTS, WITH MEASURED IMPACT ON 30-DAY RE-HOSPITALISATION RATES

Acronym: JECICA

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Sep 8, 2016
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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