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OpenTrials
Completed

NCT Number: NCT05414643

Management of Acute Cardiogenic Shock at the New Brunswick Heart Centre

In Atlantic Canada, acute myocardial infarction occurs at a rate of 2.9 % of the population and is the most common cause of cardiogenic shock (CS). In many studies, acute myocardial infarction accounts for up to 80% of the patients with CS. While there are different methods of treating patients with CS, the rate of mortality has not significantly improved over the years and remains as high as 50%. Recent studies have shown that a multi-modal, team-based approach can help improve patient outcomes; however, such a standardized approach is yet to be implemented in the New Brunswick Heart Centre (NBHC).

The study aims to understand the difference in outcomes between two groups of patients treated for CS: SHOCK TEAM versus non-SHOCK TEAM. This is a retrospective study of 168 patients using the data from NBHC registry and patient charts. The study duration is 1 year. The primary outcome is hospital survival. Secondary outcomes include time from diagnosis to invasive monitoring and intervention. All data will be analyzed statistically between the two groups. The end goal of the study is to establish standard guidelines to treat CS patients and improve patient survival.

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Key information

Conditions

Cardiogenic Shock Cardiovascular Diseases Heart Diseases Infarction Ischemia Myocardial Infarction Myocardial Ischemia Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Shock Shock, Cardiogenic Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

New Brunswick Heart Centre

Saint John, New Brunswick, E2L 4L2, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Any patient admitted to the CCU with a diagnosis of CS (SCAI groups C, D or E) at any point during their CCU care.

Exclusion criteria

  • CS patients having SCAI groups A, B (this group was used only for preliminary analysis, hence this is the exclusion criteria for all final analyses).

Treatment and study plan

Standard care

Other

No interventions were used, as this is an observational study.

Primary outcomes

  1. Percentage mortality

    Time frame: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months

    Any in-hospital mortality (within Saint John Regional Hospital, another hospital after transfer)

  2. Length of stay (LOS))

    Time frame: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months

    LOS was considered only for patients who were discharged directly home from Saint John Regional Hospital

  3. Discharge disposition

    Time frame: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months

    Discharge of patients home, transfer to another hospital or to another institution (special care home, extra-mural home)

  4. Percentage of missed opportunities

    Time frame: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months

    Missed opportunities was defined as patients who suffered significant delays or those who did not receive any intervention

Secondary outcomes

  1. Time from diagnosis of shock to in-hospital processes

    Time frame: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months

    Time gaps between the first diagnosis of a cardiogenic shock to in-hospital processes like invasive monitoring, cardiac catheterization or interventions (surgery, PCI, TAVI, IABP or ECMO).

Sponsors and collaborators

Lead sponsor

New Brunswick Heart Centre

Other

Registry information

Acronym: Team-Shock

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jun 10, 2022
Registry last updated
Jun 10, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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