Management in Intensive Care Unit of Life-threatening Keto-Acidosis

Analysis of patients with International Statistical Classification of Diseases and Related Health Problems coding compatible with inclusion

• Selection of patients eligible for inclusion based on review of medical records (verification of inclusion and non-inclusion criteria)
• Telephone contact and sending of the information letter on participation in the study and research of the patient's non-opposition to his participation and the processing of his data.
• Collection of retrospective data
• Phone call to collect prospective data

Inclusion criteria

• Major (age ≥ 18 years old)
• Hospitalized in intensive care between January 2014 and December 2023 for ketoacidosis complicated by organ failure in the participating departments.
• Diagnosis of ketoacidosis judged to be the main cause of the severity of the clinical condition.
• Blood potential hydrogen < 7.15 and bicarbonates < 10mmol/L in the first 12 hours of treatment.
• Presenting at least one of the 3 organ failures during hospitalization among:
• Use of extra-renal purification for acute renal failure
• Administration of pressor amines
• Use of mechanical ventilation

Exclusion criteria

• Metabolic acidosis primarily of an origin other than ketonic
• Refusal to participate or opposition to the processing of their data
• Patient under guardianship or curators