Management and Outcome of Fever in Children in Europe

This is an observational study assessing the management and outcome of children presenting to Emergency Departments (ED) with fever across Europe.

Completed

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Key information

Conditions

Antibiotic Prescription

Age range

Up to 18 year

Sex eligibility

All sexes

Study type

Observational

About this study

This is an observational study assessing the management and outcome of children presenting to Emergency Departments (ED) with fever across Europe. This study will use large departmental datasets to collect information on at least 50,000 febrile episodes . This study will use large-scale, pseudo-anonymized departmental data, and will not involve consented patient recruitment; nor will it use patient samples. Data included in MOFICHE will be based on that collected as part of routine clinical care. Antibiotic prescription, hospitalisation and number/type of investigations, re-attendance at ED within 5 days of the first hospital presentation will be recorded.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

aged 0- 18 years visiting the emergency care.
fever measured at ED or history of (measured) fever less than 3 consecutive days prior to presentation at emergency department

Exclusion criteria

Treatment and study plan

antibiotic prescription

Other

Primary outcomes

Antibiotic prescription

Time frame: one year

number of antibiotic prescriptions
hospitalization

Time frame: one year

number of children requiring admission to hospital
Number of investigations

Time frame: one year

number of investigations
Number of children re-attending within 5 days of the first hospital presentation.

Time frame: one year

Number of re-attendance

Sponsors and collaborators

Lead sponsor

Imperial College London

Other

Registry information

Official study title

Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)

Acronym: MOFICHE

Important dates

Study start: 2017
Primary completion: 2018
Study completion: 2021
First posted: Feb 3, 2022
Registry last updated: Feb 3, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed