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Completed

NCT Number: NCT05174715

Malnutrition Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement

Evaluation of malnutrition with the help of the GLIM criteria. Muscle mass measurement, as recommended in the GLIM criteria was done with the help of abdominal CT scan and BIA. Both methods were compared and their association to the clinical outcome was assessed.

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Key information

Conditions

Malnutrition Atrophy Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Nutrition Disorders Nutritional and Metabolic Diseases Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Sarcopenia Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

We retrospectively analysed 260 patients undergoing major abdominal surgery between January 2017 and December 2019. Patients were prospectively screened and assessed for malnutrition with Nutritional Risk Score (NRS) and Subjective Global assessment (SGA). Body composition was analysed with CT scan and BIA within 30 days before surgery. GLIM criteria were retrospectively determined referring to the Fat free Mass from BIA (FFMBIA) and Muscle Mass from axial CT scan at lumbar level 3 (MMCT). The prevalence of GLIM - malnutrition according to BIA and CT was evaluated. Multivariate logistic regression analysis was used to determine association between malnutrition and outcome parameters. ROC-curves specified sensitivity and specificity of the different tools and areas under the curve were calculated.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age above 18 years
  • BIA and CT scan was available within 31 days before surgery
  • patients undergoing major abdominal surgery for gastrointestinal cancer

Exclusion criteria

  • patients who were not able to agree to the participation
  • missing assessment of the nutritional status
  • leck of quality of the CT scan

Treatment and study plan

BIA

Other

nutritional status was evaluated using BIA

Primary outcomes

  1. overall complications

    Time frame: 31 days POD

    all complications perioperatively including surgical side infections, anastomic leakage, sepsis

Sponsors and collaborators

Lead sponsor

Klinikum St. Georg gGmbH

Other

Registry information

Official study title

Evaluation of Malnutrition in Patients Undergoing Major Abdominal Surgery Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement

Important dates

Study start
2017
Primary completion
2019
Study completion
2020
First posted
Jan 3, 2022
Registry last updated
Jan 14, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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