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OpenTrials
Completed

NCT Number: NCT02241564

Malignancies in Transplanted Patients

The aim of the project is to improve the overall treatment and outcome of renal, pancreas or liver transplanted patients who have encountered a malignancy by a structured treatment program for diagnosis and treatment of the malignancy, optimization of the immunosuppressive treatment, follow-up and evaluation of the program.

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Key information

Conditions

Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Surgery, Section of Transplantation Surgery, Uppsala University Hospital

Uppsala, SE-75185, Sweden

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients willing and capable of giving written informed consent of participation in the project
  • Patients with a previous diagnosed or presently diagnosed or reoccurrence of a malignancy (other then basal cell carcinoma)

Exclusion criteria

  • Patients with a primary liver cancer as cause of the transplantation

Treatment and study plan

Referral to a multidisciplinary expert panel at the Uppsala University Hospital after tumor detection

Other

Switch from calcineurin inhibitor to an mTOR inhibitor

Drug

Primary outcomes

  1. Patient survival

    Time frame: 12 months, 2 years, 3 years

    After inclusion

Secondary outcomes

  1. Graft survival

    Time frame: 12 months, 2 years, 3 years

    After inclusion

  2. ImmuKnow Assay value

    Time frame: 12 months

  3. Tumour progression/regression/reoccurrence

    Time frame: 12 months, 2 years, 3 years

  4. Maintained switch of immunosuppression from calcineurin inhibitor to mTOR inhibitor

    Time frame: 3 years

  5. Kidney function

    Time frame: 12 months, 2 years, 3 years

    Creatinine measure

Sponsors and collaborators

Lead sponsor

Uppsala University

Other

Registry information

Official study title

Follow-up of Malignancies in Transplanted Patients

Acronym: MALTX

Important dates

Study start
2007
Primary completion
2017
Study completion
2017
First posted
Sep 16, 2014
Registry last updated
Oct 26, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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