Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT01532739

Making Memory Better for Seniors With Mild Cognitive Impairment

The purpose of this study is to investigate the feasibility and effectiveness of a cognitive training group in individuals with Mild Cognitive Impairment, using a new paradigm that will optimize ecological validity by (1) focusing on everyday memory problems, (2) supplementing traditional memory training with the teaching of an empirically-supported problem-solving approach, and (3) employing a clinically representative sample of individuals with MCI (e.g., not excluding those with mild affective symptoms).

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Neuropsychology Service, Nova Scotia Hospital

Dartmouth, Nova Scotia, B2Y 3Z9, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of Mild Cognitive Impairment

Exclusion criteria

  • Clinical diagnosis of dementia
  • History of neurological conditions known to impair cognition
  • History of alcohol or drug abuse
  • History of chronic psychiatric illness
  • Current symptoms of moderate to severe depression (Geriatric Depression Scale >19) or anxiety (Beck Anxiety Inventory >15)

Treatment and study plan

Cognitive training

Behavioral

The cognitive training consists of 10 weekly 2-hour sessions. It is run with groups of MCI participants and their study partners (who help with reinforcing the strategies in everyday activities). The program provides information about memory and lifestyle factors in the first two weeks, followed by training and practice over the next eight weeks on empirically-supported cognitive strategies known to be effective at supporting day-to-day remembering in MCI. Participants learn to apply a core set of strategies (spaced retrieval, memory book logging) across a variety of common memory problems (e.g., remembering names, appointments, etc). To enhance the likelihood that these strategies will transfer to other settings beyond training, participants are also taught a memory problem solving approach that will cue them to recognize situations in which they need to: (1) stop and remember something, (2) select and apply an appropriate memory strategy, and (3) monitor that it is working.

Primary outcomes

  1. Change in everyday memory functioning

    Time frame: Measured at baseline and months 3, 5, 8

    Rivermead Behavioural Memory Test (3rd Edition)

Secondary outcomes

  1. Change on traditional memory testing

    Time frame: Measured at baseline and months 3, 5, 8

    California Verbal Learning Test (2nd Edition)

  2. Change in memory perception

    Time frame: Measured at baseline and months 3, 5, 8

    Multifactorial Metamemory Questionnaire

  3. Change in mood (i.e., self-report symptoms of depression)

    Time frame: Measured at baseline and months 3, 5, 8

    Geriatric Depression Scale

  4. Change in mood (i.e., self-report symptoms of anxiety)

    Time frame: Measured at baseline and months 3, 5, 8

    Beck Anxiety Inventory

  5. Change in other psychiatric symptoms (informant-report)

    Time frame: Measured at baseline and months 3, 5, 8

    Neuropsychiatric Inventory

  6. Change in quality of life

    Time frame: Measured at baseline and months 3, 5, 8

    Zarit Burden Interview

  7. Change in caregiver burden

    Time frame: Measured at baseline and months 3, 5, 8

    Zarit Burden Interview

  8. Feasibility

    Time frame: Measured at end of study

    Recruitment, retention, and compliance rates

Sponsors and collaborators

Lead sponsor

Nova Scotia Health Authority

Other

Collaborators

  • Nova Scotia Health Research Foundation

Registry information

Official study title

Neuropsychological Intervention for a Seniors Mental Health Population With Mild Cognitive Impairment

Important dates

Study start
2011
Primary completion
2025
Study completion
2025
First posted
Feb 14, 2012
Registry last updated
Aug 21, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.