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Completed

NCT Number: NCT00086385

Maintaining Nonsmoking: Older Smokers - 1

The purpose of this study was to examine pharmacological and psychological interventions for smokers over 50.

Completed

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Key information

Conditions

Tobacco Use Disorder Behavior Chemically-Induced Disorders Health Behavior Mental Disorders Smoking Cessation Substance-Related Disorders

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

San Francisco

San Francisco, California, 94143, United States

About this study

The overall goals of this line of research were to prevent relapse to cigarette smoking, and to understand the processes related to smoking and relapse. The specific aims of the current study were to test a series of hypotheses about the efficacy and cost-effectiveness of long-term, tailored interventions in chronic, older smokers and the interaction of these interventions with gender and depression. Participants were 50 years or older and smoker 10 or more cigarettes per day. Baseline assessments includes measures of smoking behavior, nicotine dependence, depression diagnosis, demographics and life circumstances and measures of anger, depression and mood disturbance, stress, social support, health status, motivation for changed and drug and alcohol use.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

smokers of at least 10 cigarettes per day

Inclusion criteria

MULTIPLE

Exclusion criteria

MULTIPLE

Treatment and study plan

Nicotine polacrilex, Bupropion

Drug

Subjects receive 12 weeks of bupropion treatment and 10 weeks of nicotine replacement.

Other names: Nicorette, Zyban

Primary outcomes

  1. Participants Abstinent From Cigarettes

    Time frame: Two years

    Primary outcome variable was 7-day point prevalence cigarette abstinence verified biochemically at week 104

Sponsors and collaborators

Lead sponsor

University of California, San Francisco

Other

Collaborators

  • National Institute on Drug Abuse (NIDA)

Registry information

Official study title

Maintaining Nonsmoking: Older Smokers

Important dates

Study start
2001
Primary completion
2009
Study completion
2009
First posted
Jul 7, 2004
Registry last updated
Mar 23, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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