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NCT Number: NCT05835817

Magnetoencephalography by Optical Pumping Magnetometer

MagnetoEncephaloGraphy (MEG) is a method of recording brain activity with high temporal resolution and good spatial resolution, compared to current recording techniques such as ElectroEncephaloGraphy (EEG). The main limitation of MEG is its cost due to the sensors used, the Super Quantum Interference Devices (SQUID). These require a complex infrastructure from an instrumentation point of view to operate, requiring liquid helium, most often at a loss, at increasing cost. Optical Pumping Magnetometers (OPM) type sensors represent a promising alternative to SQUIDs sensors, especially since they do not require helium cooling.

The purpose of this project is to Identify biomarkers in Magnetoencephalography of normal brain development in healthy adults, premature and term newborns from "a priori" obtained by the classical technique of High Resolution EEG performed.

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Key information

Conditions

Magnetoencephalography Female Urogenital Diseases and Pregnancy Complications Neonate Obstetric Labor Complications Obstetric Labor, Premature Optical Pump Magnetometer Pregnancy Complications Premature Premature Birth Urogenital Diseases

Age range

1 day and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • For healthy adult volunteers
  • Age between 18 and 65
  • No pathology, no treatment
  • No toxicant intake
  • For term newborns
  • Child between 38 and 42 weeks gestational age on the day of registration
  • No pathology, no treatment
  • For children born prematurely
  • Child between 28 and 36 weeks gestational age on the day of registration
  • No pathology, no treatment apart from routine care related to prematurity
  • For pregnant women
  • Pregnant with between 28 to 40 weeks gestational age on the day of registration
  • No pathology, no treatment

Exclusion criteria

  • Subject and Patients "not compatible" MEG. Wearers of prosthesis or pacemaker likely to generate artefacts interfering with the measurement. There is no danger to the subject, but the measurement itself may be impossible.
  • Patients who cannot stand to stand still for a few minutes.
  • Newborn on ventilatory assistance or infusion
  • Newborn baby not meeting the age criteria

Treatment and study plan

magnetoencephalography

Other

40 minutes of Magnetoencephalography with Optical Pump Magnetometer

Primary outcomes

  1. Signal to noise ratio of the MEG OPM

    Time frame: 1 day

    Signal to noise ratio of the MEG OPM is in dB

  2. Signal to noise ratio of HR EEG

    Time frame: 1 day

    Signal to noise ratio of HR EEG is in dB

  3. Number of dB between Signal to noise ratio of the MEG OPM and Signal to noise ratio of HR EEG

    Time frame: 1 day

Study contacts

Contact information is provided by the study sponsor or research team.

Fabrice Wallois, Pr

CONTACT

[email protected]

03 22 08 80 51

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Acronym: MEG OPM

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Apr 28, 2023
Registry last updated
May 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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