Magnetic Resonance Myocardial Stress Perfusion in Pediatric Patients with Cardiovascular Disease

the goal of this observational study is to evaluate myocardial ischemia and myocardial microcirculation dysfunction in children with cardiovascular disease by myocardial stress perfusion imaging.

During their disease progress, participants will undergo myocardial stress perfusion, laboratory tests when hospitalization and follow-up, and the baseline data will be collected in the admission. all the above examination data will be analysed to identify early subclinical myocardial changes and evaluate the value of magnetic resonance myocardial stress perfusion in predicting prognosis.

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Key information

Conditions

Kawasaki Disease Anomalous Origin of Coronary Artery Cardiovascular Disease Cardiovascular Diseases Hemic and Lymphatic Diseases Lymphatic Diseases Mucocutaneous Lymph Node Syndrome Skin Diseases Skin Diseases, Vascular Skin and Connective Tissue Diseases Vascular Diseases Vasculitis

Age range

Up to 18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

West China Second University Hospital, Sichuan University.

Chengdu, Sichuan, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients diagnosed with cardiovascular disease, including Kawasaki disease, anomalous origin of coronary artery, postoperative congenital heart disease.

Exclusion criteria

Mental abnormalities or poor compliance ; heart, kidney and other important organs were seriously incomplete.
MRI examination contraindications ; gadolinium contrast agent contraindications ; claustrophobia.

Treatment and study plan

Primary outcomes

Major adverse cardiovscualr events

Time frame: 10 years after the onset

Major adverse cardiovascular events including cardiac death, transient ischemic attack or stroke, myocardial infarction, arrhythmia, heart failure, severe valvular disease, percutaneous coronary intervention, coronary artery bypass graft, and other cardiovascular surgery.

Sponsors and collaborators

Lead sponsor

West China Second University Hospital

Other

Registry information

Official study title

Magnetic Resonance Myocardial Stress Perfusion: to Improve the Myocardial Evaluation in Pediatric Patients with Cardiovascular Disease

Important dates

Study start: 2024
Primary completion: 2034
Study completion: 2034
First posted: Oct 15, 2024
Registry last updated: Oct 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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