Salem Anaesthesia Pain Clinic
Surrey, British Columbia, V3S 7J1, Canada
Location status: Recruiting
Recruiting
NCT Number: NCT05862454
Magnesium Injection Ensures Steroid Avoidance During Vaccine, Viremia or Immunocompromise
Steroid injections are used for interventional pain management. However, their side-effect of immunosuppression may increase the risk of infections. Magnesium is an alternative anti-nociceptive injection that may be used instead of steroids.
Prospective observational study of patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant.
Recruiting
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Conditions
Age range
20 year–99 year
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
Corticosteroid injections are used for interventional pain management. The immunosuppression effect of steroid injection may increase the risk of infections. Magnesium is an alternative anti-nociceptive agent that may be used for interventional pain injection therapy, instead of steroids.
Prospective observational clinical study of pain clinic patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant. Data analyzed with IBM® SPSS® Statistics 25 (IBM Corp, Armonk, NY); using Student's t-test, ANOVA, Pearson Chi-square test, and regression analysis. P-value <0.05 is considered significant.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- adult chronic pain patients
- previous interventional injection therapy
- consent for interventional injection therapy
- good treatment compliance
- regular sleep diary
- regular pain diary
- informed consent for diary review
- consent for clinical record quality assurance review
Exclusion criteria
- organ insufficiency
- cognitive disorder
- inability to provide consent
- major neuropsychiatric disorder
- unreliable diary
- poor treatment compliance
- previous adverse/allergic reactions to magnesium
Treatment and study plan
Magnesium
DrugMagnesium injection therapy
Other names: Magnesium injection
Primary outcomes
-
Pain score, objective measurement using the validated Numeric Pain Rating scale
Time frame: 12 weeks
Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain
Secondary outcomes
-
Sleep quality score, objective measurement using the validated Likert sleep scale
Time frame: 12 weeks
Sleep quality score, using the Likert sleep scale of 0 to 10, low scores indicate poor sleep, high scores indicate better sleep
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Salem Anaesthesia Pain Clinic
Other
Registry information
Official study title
Magnesium Injection Ensures Analgesia and Steroid Avoidance During Vaccination, Viremia or Immunocompromise
Important dates
- Study start
- 2020
- Primary completion
- 2025
- Study completion
- 2025
- First posted
- May 17, 2023
- Registry last updated
- Jan 27, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.