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Active, Not Recruiting

NCT Number: NCT05947760

Magnesium as an Adjuvant Agent for Postoperative Pain

Participants are being asked to participate in this research study because they have elected to undergo periacetabular osteotomy (PAO). This research study is looking at if using IV magnesium during surgery can help to reduce pain after surgery.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Pain, Postoperative Neurologic Manifestations Pain Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

14 year–89 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

University Hospitals

Cleveland, Ohio, 44106, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing periacetabular osteotomy with or without adjuvant hip arthroscopy

Exclusion criteria

  • illiterate or non-English speaking patients
  • patients with 2nd or 3rd degree AV block
  • patients with severe renal insufficiency
  • patients with heart failure
  • patients with bradycardia

Treatment and study plan

IV Magnesium Sulfate

Drug

Participants will receive IV Magnesium Sulfate intraoperatively.

Primary outcomes

  1. Change in pain as measured by the Visual Analog Scale (VAS)

    Time frame: Over the first 7 days post operatively, measured every 6 hours

    The VAS is a scale from 0-10 with 0 being no pain and 10 being the worst pain ever

  2. Change in number of narcotic medications consumed as measured by the medical record review

    Time frame: Over the first 7 days post operatively, gathered every 6 hours.

Secondary outcomes

  1. Change in PROMIS scores

    Time frame: 2 weeks, 6 weeks, 3 months, 6 months, 1 year

    The PROMIS is a 14 item questionnaire is a set of person-centered measures that evaluates and monitors physical, mental, and social health in adults and children. It can be used with the general population and with individuals living with chronic conditions. Scores are typically between 20-80, but may be 0-100.

  2. Change in modified Harris Hip Scores (mHHS)

    Time frame: 2 weeks, 6 weeks, 3 months, 6 months, 1 year

    The mHHS is a scoring system for functional outcomes post periactabular osteotomies that has a scale of 0-100, 0 being the lowest functional outcome and 100 being the highest

Sponsors and collaborators

Lead sponsor

University Hospitals Cleveland Medical Center

Other

Registry information

Official study title

Magnesium as an Adjuvant Agent for Postoperative Pain Control Following Periacetabular Osteotomy

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 17, 2023
Registry last updated
Apr 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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