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OpenTrials
Completed

NCT Number: NCT06148675

Macrowire for IntracraNial Thrombectomy

The aim of this study is to develop a multicenter database of patient data and outcomes for patients undergoing intracranial thrombectomy for acute ischemic stroke secondary to emergent large vessel occlusion with delivery of reperfusion catheter over a novel macrowire (Aristotle Colossus) to perform intracranial mechanical thrombectomy.

Completed

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Key information

Conditions

Stroke, Acute Ischemic Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Ischemic Stroke Nervous System Diseases Stroke Vascular Diseases

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Indiana University Methodist Hospital

Indianapolis, Indiana, 46202, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age >18-85 years Time of onset < 24 hours Acute stroke patient with NIHSS >6 CT-ASPECTS ≥ 6 Proven intracranial occlusion - (ICA-T, M1) Modified Rankin score: 0-2

Exclusion criteria

Age <18 years or >85 years Unknown time of onset NIHSS < 5 CT ASPECTS <5 Pre-stroke morbidity, modified Rankin score > 2 Tandem occlusion

Treatment and study plan

No intervention

Other

No intervention,data collection

Primary outcomes

  1. Ability to deliver reperfusion catheter to the intracranial occlusion with macrowire alone (Yes/No)

    Time frame: Intraprocedure

Secondary outcomes

  1. Time from vascular access to first intracranial pass (minutes)

    Time frame: Procedure duration

  2. Time from vascular access to recanalization (minutes)

    Time frame: Procedure duration

  3. Vessel dissection (Yes/No)

    Time frame: Intraprocedure

Sponsors and collaborators

Lead sponsor

Indiana University

Other

Registry information

Official study title

MINT Registry : Macrowire for IntracraNial Thrombectomy

Acronym: MINT

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Nov 28, 2023
Registry last updated
Nov 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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