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Completed

NCT Number: NCT07522853

M-TAPA vs OSTAP for Postoperative Analgesia in Laparoscopic Inguinal Hernia

This randomized controlled trial aims to compare the postoperative analgesic efficacy of M-TAPA block and OSTAP block in patients undergoing laparoscopic inguinal hernia repair. Pain scores, analgesic consumption, and patient satisfaction will be evaluated.

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Key information

Conditions

Inguinal Hernia Bilateral Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Postoperative Pain Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kartal Dr. Lütfi Kırdar City Hospital

Istanbul, Turkey (Türkiye)

About this study

Prospective, randomized, single-blind, controlled study including 90 patients undergoing elective laparoscopic inguinal hernia repair. Patients will be randomized into three groups: M-TAPA, OSTAP, and control. Postoperative pain scores (VAS), analgesic consumption, time to first analgesic requirement, and patient satisfaction will be assessed over 24 hours.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged between 18 and 65 years
  • American Society of Anesthesiologists (ASA) physical status I-II
  • Scheduled for elective laparoscopic inguinal hernia repair (TEP technique)
  • Ability to understand and use the Visual Analog Scale (VAS)
  • Provided written informed consent

Exclusion criteria

  • Refusal to participate or inability to provide informed consent
  • Age under 18 or over 65 years
  • ASA physical status ≥ III
  • Coagulopathy (including abnormal INR, thrombocytopenia, or platelet dysfunction)
  • Infection at the injection site
  • Known allergy or hypersensitivity to study medications (local anesthetics, NSAIDs, opioids)
  • Chronic opioid use (longer than 4 weeks)
  • Use of psychiatric medications affecting pain perception
  • Inability to cooperate or communicate effectively
  • Requirement for postoperative intensive care

Treatment and study plan

Modified Thoracoabdominal Nerve Block through perichondrial approach (M-TAPA)

Procedure

Ultrasound-guided bilateral M-TAPA block performed with 20 mL of 0.25% bupivacaine per side

Oblique Subcostal Transversus Abdominis Plane Block (OSTAP)

Procedure

Ultrasound-guided bilateral OSTAP block performed with 20 mL of 0.25% bupivacaine per side

Standard Analgesia use (paracetamol, contramal)

Other

Patients received standard postoperative analgesia without regional block

Primary outcomes

  1. Total analgesic consumption in 24 hours

    Time frame: 24 hours postoperative

    Total amount of dexketoprofen consumed in the first 24 hours after surgery

Secondary outcomes

  1. Postoperative Pain Intensity (VAS Score)

    Time frame: 0 (15 minutes), 2, 4, 8, 12, 16, and 24 hours postoperative

    Postoperative pain intensity assessed using the Visual Analog Scale (VAS, 0-10), where 0 indicates no pain and 10 indicates worst imaginable pain.

  2. Time to First Analgesic Requirement

    Time frame: Within 24 hours postoperative

    Time from the end of surgery to the first request for analgesic medication

  3. Tramadol Consumption

    Time frame: 24 hours postoperative

    Total amount of tramadol administered within the first 24 hours after surgery.

  4. Patient Satisfaction Score

    Time frame: 24 hours postoperative

    Patient satisfaction assessed using a Likert scale evaluating overall satisfaction with postoperative pain management

  5. Incidence of Postoperative Nausea and Vomiting

    Time frame: 24 hours postoperative

    Incidence of nausea and vomiting observed during the first 24 hours after surgery.

Sponsors and collaborators

Lead sponsor

Dr. Lutfi Kirdar Kartal Training and Research Hospital

Other Gov

Registry information

Official study title

Laparoscopic Inguinal Hernia Surgery Patients: Comparison of Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) and Oblique Subcostal TAP Block for Postoperative Analgesia

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 13, 2026
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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