Lutein Influence on Macula of Persons Issued From Amd Parents

The objective of this study is to estimate the efficiency of a nutritonal supplementation with lutein and zeaxanthin to increase their plasma concentration and the density of macular pigment, in subjects at high genetic risk for AMD (1st generation stemming from parent affected by DMLA). This study is a multicentric, double blind, randomized clinical trial of supplementation versus placebo

Inclusion criteria

• Men or women 40 to 70 years old
• Presenting histories of wet AMD with their father or their mother or 2
• Visual acuity of 20/25 or better (ETDRS)
• The presence of a AMD in one eye is possible
• Enlightened consent writes, dated and signed by the participant and the investigator above all examination required by the research.
• Subject agreeing to be registered in the national file
• Affiliated or profitable subject of a national insurance scheme

Exclusion criteria

• Presence of signs of AMD in both eyes (if AMD in one eye, inclusion for the other eye is possible)
• Histories of the other evolutionary eye pathologies susceptible to complicate the evaluation of the AMD and of the visual acuity (severe glaucoma, strong nearsightedness (superior or more equal in - 6 dioptres), the other severe rétinopathie)
• Subject with history of cataract surgery
• Opaqueness preventing the evaluation of the photos of the retina (cataract, corneal dystrophy)
• Supplementation with food complements in the year which precedes (cf. appendix 2 of the protocol)
• Participation in another clinical trial during 30 days which precede
• Subjects not compliants
• Subjects not flatware by the system of social security
• Subjects under guardianship judicial