Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

This project will conduct a series of analysis of physiological and clinical data on tracheostomy patients who receive prolonged mechanical ventilation, hoping to find out the different manifestations of patients through the investigation by a variety of physiologic measurements, so as to understand whether different types of patients phenotype to derive different clinical strategies for liberation of the mechanical ventilator.

Recruiting

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Key information

Conditions

Prolonged Mechanical Ventilation Pathologic Processes Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Aspiration Respiratory Tract Diseases

Age range

20 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

National Taiwan University Hospital

Taipei, Taiwan

Location status: Recruiting

Location contact

Jih-Shuin Jerng, MD, PhD

CONTACT

[email protected]

+886-2-23123456 ext. 263532

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with at least 10 days of mechanical ventilation at the intensive care unit of National Taiwan University Hospital and transferred to the Respiratory Care Center of National Taiwan University Hospital for weaning training
Patients who have undergone tracheostomy and still have a tracheotomy tube
Are at least 20 years old
Stable respiratory condition with inspired oxygen fraction not exceeding 50%

Exclusion criteria

Hemodynamic instability or continuous use of vasopressors
Pregnancy

Treatment and study plan

Primary outcomes

Liberation from mechanical ventilation at discharge from the weaning unit

Time frame: Five days

At least five consecutive days of free from mechanical ventilation ventilation

Study contacts

Contact information is provided by the study sponsor or research team.

Jih-Shuin Jerng, MD, PhD

CONTACT

[email protected]

+886-2-23123456 ext. 263532

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

The Difference and Prognostic Significance of Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

Important dates

Study start: 2022
Primary completion: 2025
Study completion: 2025
First posted: Dec 1, 2022
Registry last updated: Dec 30, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed