Lung Ultrasound Changes in Covid 19 Patients Discharged From Hospital

Lung ultrasound has been used to help diagnose COVID-19 as an alternative to CT scanning and chest X-ray. CT scanning is onerous and there are difficulties taking critically unwell patients there as well as decontamination issues.

Chest X-ray misses up to 40% of COVID diagnoses. Although lung ultrasound can diagnose, the investigators do not know how long these lung ultrasound changes last. The investigators would like to follow up patients to characterise the pattern of changes and how long they last. This is particularly important given a potential second surge of COVID-19 is looming and the investigators would like to know if lung ultrasound changes are new or old in patients presenting during this second wave and in the future.

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Key information

Conditions

Covid19 COVID-19 Coronaviridae Infections Coronavirus Coronavirus Infection Coronavirus Infections Infections Lung Diseases Nidovirales Infections Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections SARS-CoV Infection Severe Acute Respiratory Syndrome Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chelsea and Westminster Hospital

London, Greater London, SW10 9NH, United Kingdom

About this study

Ultrasound has been invaluable during this pandemic to diagnose COVID-19. The investigators have used it alongside CT scanning to rationalise the number of CT scans especially when patients are unstable. The investigators do not know how long these changes last on lung ultrasound after discharge and the investigators wish to study this.

This is because patients will start presenting shortly who have a history of COVID-19 with acute medical problems and if the investigators are to use lung ultrasound again the investigators would like to know whether the changes the investigators see are new or old.

This is vitally important before a second surge and especially so before winter. This may also facilitate triage of patients from the front door in the Emergency department to different areas (such as COVID-19 zones or clean areas).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 years old or older
Confirmed COVID-19 positive with changes on CXR or CT scan
Having had an initial lung ultrasound in the Emergency department when they were first admitted into the hospital.

Exclusion criteria

Pre-existing lung disease
Heart failure
Under 18 years old.

Treatment and study plan

Primary outcomes

Assessment of lung ultrasound changes over the time period of follow up.

Time frame: Approximately 3 months or until the ultrasound changes in the lung had normalised

The assessment will determine how long it takes for lung ultrasound changes to resolve following discharge from hospital in patients who were diagnosed with COVID-19 (unit of measurement: days).

Secondary outcomes

Exploration of ongoing symptoms

Time frame: Approximately 3 months or until the ultrasound changes in the lung had normalised

Ongoing symptoms will be explored by using screening questions.

Sponsors and collaborators

Lead sponsor

Chelsea and Westminster NHS Foundation Trust

Other

Registry information

Official study title

Prospective Observational Study Looking at Lung Ultrasound Changes During Recovery From COVID19 Infection

Important dates

Study start: 2020
Primary completion: 2020
Study completion: 2020
First posted: Sep 30, 2021
Registry last updated: Oct 8, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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